Results 91 to 100 of about 385,028 (263)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Integrating Drought Stress Signaling and Smart Breeding for Climate-Resilient Crops: Regulatory Mechanisms and Genetic Strategies

open access: yesPlants
The escalating frequency and severity of drought events pose significant threats to agricultural productivity and food security. Drought stress not only restricts crop growth and yields but also destabilizes agricultural ecosystems.
Mingyu Wang   +3 more
doaj   +1 more source

Production of wheat-doubled haploids resistant to eyespot supported by marker-assisted selection

open access: yesElectronic Journal of Biotechnology, 2019
Background: Wheat is one of the most important crops cultivated all over the world. New high-yielding cultivars that are more resistant to fungal diseases have been permanently developed.
Halina Wiśniewska   +10 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Molecular marker assisted selection for increasing inbreeding in S1 populations of cassava

open access: yesAnais da Academia Brasileira de Ciências
The objective of the present work was to use MAS in self-pollinated cassava populations for obtaining individuals with high inbreeding (f) aimed at rapid development of partial inbred lines.
PAULO HENRIQUE G.A. DE OLIVEIRA   +4 more
doaj   +1 more source

Molecular Breeding for Rainfed Lowland Rice in the Mekong Region

open access: yesPlant Production Science, 2005
In the past 20 years, the rice-breeding program in Thailand had little success in developing new cultivars to replace Kao Dawk Mali 105 (KDML105) and Kao Khor 6 (RD6) for the rainfed lowland rice environments. The main reason for the poor adoption of new
Theerayut Toojinda   +7 more
doaj   +1 more source

Diameter-Selective Dispersion of Carbon Nanotubes via Polymers: A Competition between Adsorption and Bundling

open access: yes, 2015
The mechanism of the selective dispersion of single-walled carbon nanotubes (CNTs) by polyfluorene polymers is studied in this paper. Using extensive molecular dynamics simulations, it is demonstrated that diameter selectivity is the result of a ...
Arianna Filoramo   +6 more
core   +5 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

QTL mapping associated with rooting stem cuttings from Citrus sunki vs. Poncirus trifoliata hybrids

open access: yesCrop Breeding and Applied Biotechnology, 2003
The citrus vegetative propagation by stem cuttings depends on factors such as genetics, age, vigor, woodiness, growth regulators, environment and nutrition.
Amauri Siviero   +2 more
doaj  

Development of "Xiangruan Zaogeng" National Day rice by molecular marker assisted selection

open access: yes上海师范大学学报. 自然科学版
In order to obtain high-quality fragrant and soft National Day rice suitable for cultivation in Shanghai, "Songzaoxiang No.1" and "Shangshi Zaozaoxiang" crossed to produce F1, which was self-crossed till F4, accompanied simultaneously by soft rice gene ...
LIU Xiaoyan   +4 more
doaj   +1 more source

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