An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The effect of the bovine major histocompatibility complex (BoLA) locus on animal health may be due to a direct action of its alleles on immune functions, whereas its indirect effect on production traits might be explained by the better general health ...
Carlos Souza do Nascimento +10 more
doaj +1 more source
Collaborative project between CIAT and Cirad rice improvement through the use of synthetic populations [PDF]
The Cirad/CIAT rice collaborative project focuses on the development and enhancement of rice synthetic populations through recurrent selection (RS) with the goal to develop and diffuse improved material, populations or lines, for various rainfed ...
Audebert, Alain +6 more
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
High-yield hybrid breeding of Camellia oleifolia based on ISSR molecular markers
Background C. Oleifera is among the world’s largest four woody plants known for their edible oil production, yet the contribution rate of improved varieties is less than 20%.
Jinjia Zheng +6 more
doaj +1 more source
Development of isogenic lines for resistance to Septoria tritici blotch in wheat
Septoria tritici blotch (STB), caused by the fungus Mycosphaerella graminicola (asexual stage: Septoria tritici), is one of the most economically important diseases of wheat worldwide.
S.B. GOODWIN, I. THOMPSON
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Application of QTL mapping for early selection on growth and latex yield traits in rubber breeding [PDF]
The objective of this study was to apply the QTL mapping by Markers-Assisted Selection approach for early selection on growth and latex yield in rubber breeding.
Clément-Demange, André +5 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Gombarezisztencia gének térképezése szőlőben = Mapping resistance genes against fungi in grapevine [PDF]
Lisztharmat (PM) és peronoszpóra (DM) rezisztencia génekkel kapcsolt markerek szelekcióra való alkalmasságát vizsgáltuk szőlő inter-és intraspecifikus térképezési populációiban.
Galli, Zsolt +7 more
core

