Results 61 to 70 of about 142,606 (227)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Genetic Basis and Identification of Candidate Genes for Drought Tolerance in Oryza sativa L. by DNA Molecular-assisted Selection

open access: yesAgricultural Science Digest - A Research Journal
Background: Drought stress represents a major obstacle to ensuring worldwide agricultural output and food availability. As a primary dietary staple, rice is highly vulnerable to insufficient water, suffering significant productivity declines under drought pressure.
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Molecular marker assisted selection for increasing inbreeding in S1 populations of cassava

open access: yesAnais da Academia Brasileira de Ciências
The objective of the present work was to use MAS in self-pollinated cassava populations for obtaining individuals with high inbreeding (f) aimed at rapid development of partial inbred lines.
PAULO HENRIQUE G.A. DE OLIVEIRA   +4 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Development of "Xiangruan Zaogeng" National Day rice by molecular marker assisted selection

open access: yes上海师范大学学报. 自然科学版
In order to obtain high-quality fragrant and soft National Day rice suitable for cultivation in Shanghai, "Songzaoxiang No.1" and "Shangshi Zaozaoxiang" crossed to produce F1, which was self-crossed till F4, accompanied simultaneously by soft rice gene ...
LIU Xiaoyan   +4 more
doaj   +1 more source

Production of wheat-doubled haploids resistant to eyespot supported by marker-assisted selection

open access: yesElectronic Journal of Biotechnology, 2019
Background: Wheat is one of the most important crops cultivated all over the world. New high-yielding cultivars that are more resistant to fungal diseases have been permanently developed.
Halina Wiśniewska   +10 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

QTL mapping associated with rooting stem cuttings from Citrus sunki vs. Poncirus trifoliata hybrids

open access: yesCrop Breeding and Applied Biotechnology, 2003
The citrus vegetative propagation by stem cuttings depends on factors such as genetics, age, vigor, woodiness, growth regulators, environment and nutrition.
Amauri Siviero   +2 more
doaj  

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