Results 51 to 60 of about 6,155,889 (255)

Molecular markers: their use in tree improvement

open access: yesJournal of Forest Science, 2012
Earlier breeders used phenotypic selection based on morphological characteristics to improve tree varieties. These selections often take many cycles of breeding and backcrossing in order to place desired characteristics. But today the knowledge has paved
R. Mahajan, P. Gupta
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Simulation of marker-assisted recurrent selection in autogamous species

open access: yesCrop Breeding and Applied Biotechnology, 2002
This work used computer simulation to evaluate marker-assisted selection (MAS) in recurrent selection of autogamous species. Base populations were simulated by crossing each of five inbred lines with two others.
Eduardo Bearzoti, Roland Vencovsky
doaj  

Association of the bovine major histocompatibility complex (BoLA) BoLA-DRB3 gene with fat and protein production and somatic cell score in Brazilian Gyr dairy cattle (Bos indicus)

open access: yesGenetics and Molecular Biology, 2006
The effect of the bovine major histocompatibility complex (BoLA) locus on animal health may be due to a direct action of its alleles on immune functions, whereas its indirect effect on production traits might be explained by the better general health ...
Carlos Souza do Nascimento   +10 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Assisted-selection Of Naturally Caffeine-free Coffee Cultivars-characterization Of Snps From A Methyltransferase Gene

open access: yes, 2017
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Breeding of caffeine-free coffee cultivars require tools for an early selection of progenies bearing this later trait.
Patricia; da Silva   +9 more
core   +2 more sources

MOLECULAR MARKERS: IMPLEMENTATION IN CROP PLANT BREEDING FOR IDENTIFICATION, INTROGRESSION, AND GENE PYRAMIDING

open access: yesВавиловский журнал генетики и селекции, 2014
Over the past decades, wide theoretical and practical experience has been obtained in application of DNA markers for investigation of plant genetic diversity, construction of molecular genetic maps, mapping of genes and quantitative trait loci, and ...
I. N. Leonova
doaj  

Development of isogenic lines for resistance to Septoria tritici blotch in wheat

open access: yesCzech Journal of Genetics and Plant Breeding, 2011
Septoria tritici blotch (STB), caused by the fungus Mycosphaerella graminicola (asexual stage: Septoria tritici), is one of the most economically important diseases of wheat worldwide.
S.B. GOODWIN, I. THOMPSON
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Prediction of haplotypes for ungenotyped animals and its effect on marker-assisted breeding value estimation [PDF]

open access: yes, 2010
Background: In livestock populations, missing genotypes on a large proportion of animals are a major problem to implement the estimation of marker-assisted breeding values using haplotypes.
Calus, M.P.L.   +5 more
core   +1 more source

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