Results 101 to 110 of about 37,287 (222)
Different evolutionary paths to complexity for small and large populations of digital organisms
A major aim of evolutionary biology is to explain the respective roles of adaptive versus non-adaptive changes in the evolution of complexity. While selection is certainly responsible for the spread and maintenance of complex phenotypes, this does not ...
Adami, Christoph, LaBar, Thomas
core +4 more sources
Digital Twins in Translational Research and Health Care: An Anthropological Perspective
ABSTRACT In this essay, I consider the “social life” of digital twins in translational medicine, exploring how the United States is culturally unprepared for the arrival of digital twins at whole person scales. By looking more closely at our anticipated individual and collective interactions with digital twins for biomedical research and health care ...
Jennifer K. Wagner
wiley +1 more source
Proximity data, traditionally used for inferring social networks, can inform utilization distribution at a fine scale. Using a sampling grid approach, it is possible to identify activity hotspots and spatial dynamics in conservation‐priority habitats. ABSTRACT Understanding spatial patterns in small, elusive species is critical for behavioral ecology ...
Jesús R. Hernández‐Montero +4 more
wiley +1 more source
The 10–23 DNAzyme in Biosensing and Diagnostics: Applications, Challenges, and Future Directions
This review focuses on the 10–23 DNAzyme in diagnostics, spanning unregulated and regulated target‐recognition modes, and their functionalization across colorimetric, fluorescent, electrochemical, electrochemiluminescent, and intracellular biosensing strategies.
Connor Nurmi +5 more
wiley +2 more sources
BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
The need for the early detection of emerging pathogenic viruses and their newer variants has driven the urgent demand for developing point-of-care diagnostic tools. Although nucleic acid-based methods such as reverse transcription-quantitative polymerase
Asfia Sultana +5 more
doaj +1 more source
Detection of Naja atra Cardiotoxin Using Adenosine-Based Molecular Beacon
This study presents an adenosine (A)-based molecular beacon (MB) for selective detection of Naja atra cardiotoxin (CTX) that functions by utilizing the competitive binding between CTX and the poly(A) stem of MB to coralyne.
Yi-Jun Shi +3 more
doaj +1 more source
ABSTRACT Background and Aim Ferroptosis signaling pathway has been revealed to play a biological role in the tumorigenesis of colorectal cancer (CRC). Our aim was to evaluate the expression pattern and clinical potentials of two ferroptosis‐related genes FSP1 and ACSL4 in colorectal tumors.
Afsaneh Fardsanei +4 more
wiley +1 more source
We report a novel approach to genotyping single nucleotide polymorphisms (SNPs) using molecular beacons in conjunction with a suspended core optical fiber (SCF).
Linh Viet Nguyen +6 more
doaj +1 more source
Efferocytosis: Signaling Pathways and New Therapeutic Strategies for Diseases
1. Efferocytosis coordinates molecular signaling and metabolic reprogramming to resolve inflammation. 2. Efferocytosis dysfunction underlies four conserved pathological hallmarks across diseases. 3. Therapeutic strategies targeting efferocytosis should be context‐dependent: enhance or inhibit based on disease type. ABSTRACT Efferocytosis—the phagocytic
Lei Wang +6 more
wiley +1 more source
Dawei Deng,* Yang Li,* Jianpeng Xue, Jie Wang, Guanhua Ai, Xin Li, Yueqing GuDepartment of Biomedical Engineering, China Pharmaceutical University, Nanjing, People’s Republic of China*These authors contributed equally to this workAbstract ...
Deng D +6 more
doaj

