Results 81 to 90 of about 37,287 (222)

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Rewiring the Technological Future of Information and Biology With Nucleic Acid Information Materials

Transformative Chemistry, EarlyView.
Nucleic acid information materials (NAIMs) repurpose DNA from genetic carriers into programmable matter, integrating biotechnology with information technology to rewire the future of molecular computing, ultra‐dense data storage, and intelligent medicine.
Fangfei Yin, Fei Wang, Xiaolei Zuo, Chunhai Fan   +3 more
wiley   +1 more source

Identification and imaging of miR-155 in the early screening of lung cancer by targeted delivery of octreotide-conjugated chitosan-molecular beacon nanoparticles

Drug Delivery, 2018
Lung cancer is still the most common cancer globally. Early screening remains the key to improve the prognosis of patients. There is currently a lack of specific and sensitive methods for early screening of lung cancer.
Hai-Zhen Zhu, Jing Hou, Yi Guo, Xin Liu, Fei-Long Jiang, Guang-Peng Chen, Xiu-Feng Pang, Jian-Guo Sun, Zheng-Tang Chen   +8 more
doaj   +1 more source

The DNA/RNA autophagy protein SIDT2 as a novel neuropathological hallmark in Huntington disease

Brain Pathology, EarlyView.
SIDT2‐immunoreactive inclusions are observed in the striatum, cerebral cortex, and hypothalamus in HD cases with different Vonsattel grades, and the frequency of SIDT2‐immunoreactive inclusions is associated with longer CAG repeats in the huntingtin gene.
Sanaz Gabery, Sofia Bergh, Chrisovalantou Huridou, Rachel Y. Cheong, Barbara Baldo, Paul Günther Scheunemann, Marie‐Louisa Schoebel, Linda Holmquist Mengelbier, Elisabet Englund, Catriona McLean, Carsten Saft, Deniz Kirik, Maria Björkqvist, Glenda Halliday, Elisabeth Petrasch‐Parwez, Huu Phuc Nguyen, Jonasz Jeremiasz Weber, Åsa Petersén   +17 more
wiley   +1 more source

Detection of a Target Nucleic Acid by Ligation‐Assisted Fluorescence Enhancement of a Peptide Nucleic Acid (PNA) Twin Probe via Disulfide Binding

Biopolymers, Volume 117, Issue 4, July 2026.
Target‐induced disulfide ligation of PNA twin probes promotes pyrene excimer formation for nucleic acid detection. ABSTRACT The development of methods for detecting specific nucleic acids is important for early diagnosis and treatment of diseases at the genetic level.
Yutaka Ouchi, Koki Ishii, Yumiko Sato, Yoshitane Imai, Hideo Matsui, Takashi Ohtsuki, Yoshiyuki Hakata, Hajime Shigeto, Shohei Yamamura, Mizuki Kitamatsu   +9 more
wiley   +1 more source

Molecular beacon probes-base multiplex NASBA Real-time for detection of HIV-1 and HCV

Iranian Journal of Microbiology, 2012
Background and Objectives: Developed in 1991, nucleic acid sequence-based amplification (NASBA) has been introduced as a rapid molecular diagnostic technique, where it has been shown to give quicker results than PCR, and it can also be more sensitive ...
S Mohammadi-Yeganeh, M Paryan, S Mirab Samiee, V Kia, H Rezvan   +4 more
doaj  

Aptamer Conformation Switching-Induced Two-Stage Amplification for Fluorescent Detection of Proteins

Sensors, 2018
Basing on the conformation change of aptamer caused by proteins, a simple and sensitive protein fluorescent assay strategy is proposed, which is assisted by the isothermal amplification reaction of polymerase and nicking endonuclease.
Qiao Yu, Fenfen Zhai, Hong Zhou, Zonghua Wang   +3 more
doaj   +1 more source

Long range laser traversing system [PDF]

A study was carried out to determine the feasibility of a man-portable receiver system for land survey, which would be capable of detecting the optical scatter due to molecular and aerosol constituents of the atmosphere from a vertical laser beam.
Caudill, L. O.
core   +1 more source

Viral Pathogens Threatening Cage‐Cultured Nile Tilapia in Lake Victoria: Epidemiology, Emerging Risks and Integrated Health Management Strategies

Aquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
ABSTRACT The rapid expansion of cage culture for Nile tilapia (Oreochromis niloticus) in Lake Victoria is central to food security and profitable development in East Africa. Nevertheless, viral conditions affect the sustainability of this sector, with significant imbalances in livelihood, trade and aquaculture adaptability.
Richard S. Komba, Chacha J. Mwita
wiley   +1 more source

A Turn-on Fluorescence Sensor for Heparin Detection Based on a Release of Taiwan Cobra Cardiotoxin from a DNA Aptamer or Adenosine-Based Molecular Beacon

Molecules, 2018
This study presents two sensitive fluorescent assays for sensing heparin on the basis of the electrostatic interaction between heparin and Naja naja atra cardiotoxin 3 (CTX3). Owing to CTX3-induced folded structure of an adenosine-based molecular beacon (
Yi-Jun Shi, Liang-Jun Wang, Yuan-Chin Lee, Chia-Hui Huang, Wan-Ping Hu, Long-Sen Chang   +5 more
doaj   +1 more source