Results 41 to 50 of about 1,822,561 (192)

The molecular biology of arteriviruses.

open access: yesJournal of General Virology, 1998
.The establishment of an arterivirus family acknowledgesthemanyuniquebiologicalandmolecularpropertiesofitsfourpresent members. On the other hand, the affiliation with thecoronavirusesrecognizesanintriguingancestralrelationshipatthelevelofgenomeorganizationandreplication.ThegenomesequencesofEAV,PRRSV,LDVandSHFVwereinstrumentalin uniting and reclassifying ...
Snijder, E.J., Meulenberg, J.J.
openaire   +4 more sources

Core Fermentation (CoFe) granules focus coordinated glycolytic mRNA localization and translation to fuel glucose fermentation

open access: yesiScience, 2021
Summary: Glycolysis is a fundamental metabolic pathway for glucose catabolism across biology, and glycolytic enzymes are among the most abundant proteins in cells. Their expression at such levels provides a particular challenge.
Fabian Morales-Polanco   +13 more
doaj  

Histidine-Rich Glycoprotein Inhibits High-Mobility Group Box-1-Mediated Pathways in Vascular Endothelial Cells through CLEC-1A

open access: yesiScience, 2020
Summary: High-mobility group box-1 (HMGB1) protein has been postulated to play a pathogenic role in severe sepsis. Histidine-rich glycoprotein (HRG), a 75 kDa plasma protein, was demonstrated to improve the survival rate of septic mice through the ...
Shangze Gao   +10 more
doaj  

Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death

open access: yesiScience, 2022
Summary: Pathogen recognition and TNF receptors signal via receptor interacting serine/threonine kinase-3 (RIPK3) to cause cell death, including MLKL-mediated necroptosis and caspase-8-dependent apoptosis. However, the post-translational control of RIPK3
Daniel Frank   +23 more
doaj  

Base editing-coupled survival screening enabled high-sensitive analysis of PAM compatibility and finding of the new possible off-target

open access: yesiScience, 2021
Summary: Base editing (BE) is a promising genome engineering tool for modifying DNA or RNA and has been widely used in various microorganisms as well as eukaryotic cells.
Tianyuan Su   +6 more
doaj  

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