Results 121 to 130 of about 319,701 (282)
Algorithmic Challenges in Computational Molecular Biophysics
Journal of Computational Physics, 1999 Computational techniques for modeling large biological molecules have emerged rapidly in recent years as an important complement to experiment. Computer-generated models and simulation data are essential for analyzing structural and kinetic details that are difficult to capture experimentally for large, floppy macromolecules in solution.
Schlick, Tamar +6 more
openaire +2 more sources
Thermofluidic chip containing virtual thermal wells
Engineering Biology, 2019 The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site ...
Andrew J. Ferguson +6 more
doaj +1 more source
eSPC: an online data-analysis platform for molecular biophysics. [PDF]
Acta Crystallogr D Struct Biol, 2021 Burastero O +5 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird +8 more
wiley +1 more source
eLifeType II nuclear receptors (T2NRs) require heterodimerization with a common partner, the retinoid X receptor (RXR), to bind cognate DNA recognition sites in chromatin. Based on previous biochemical and overexpression studies, binding of T2NRs to chromatin
Liza Dahal +5 more
doaj +1 more source
Data model for biopart datasheets
Engineering Biology, 2018 This study introduces a new data model, based on the DICOM-SB (see glossary of terms for definition of acronyms) standard for synthetic biology, that is capable of describing/incorporating the data, metadata and ancillary information from detailed ...
Iñaki Sainz de Murieta +2 more
doaj +1 more source
Liquid-liquid phase separation of tau: From molecular biophysics to physiology and disease. [PDF]
Protein Sci, 2021 Rai SK +4 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid +6 more
wiley +1 more source
Bioinspired Stabilization of Fluorescent Au@SiO2 Tracers for Multimodal Biological Imaging
Advanced Functional Materials, EarlyView.This study demonstrates a bioinspired stabilization strategy for fluorescent gold‐silica nanoparticles. Inspired by natural biosilica maturation, high‐temperature calcination transforms the silica shells, preventing dissolution in cell culture media and intracellular environments.
Wang Sik Lee +5 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Here, a biointerface membrane engineered with site‐specific interfacial properties is developed. During implantation between gingival and bone defect, the membrane creates a pro‐osteogenic microenvironment, precisely modulates cellular activities at each biointerface, and facilitates the orchestration of complex healing events, ultimately leading to ...
Yuwei Zhu +13 more
wiley +1 more source