Results 31 to 40 of about 3,587,617 (298)

Gi/o protein-coupled receptor inhibition of beta-cell electrical excitability and insulin secretion depends on Na+/K+ ATPase activation

Nature Communications, 2022
Gi/o protein-coupled receptors (Gi/o-GPCRs) limit β-cell insulin secretion by decreasing Ca2+ entry; however, the underlying mechanism has not been identified. Here, the authors show that Gi/o-GPCRs hyperpolarize mouse and human β-cell membrane potential
Matthew T. Dickerson, Prasanna K. Dadi, Karolina E. Zaborska, Arya Y. Nakhe, Charles M. Schaub, Jordyn R. Dobson, Nicole M. Wright, Joshua C. Lynch, Claire F. Scott, Logan D. Robinson, David A. Jacobson   +10 more
doaj   +1 more source

Biophysics: Concepts and Fields [PDF]

, 2013
There is an idiom that “biophysicist is who discusses about biology when meets physicist, talks about physics when meets biologist and says joke when meets another biophysicist”. This idiom points to multidisciplinary nature of biophysics but what really
Amani, Mojtaba
core   +1 more source

Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami

eLife, 2022
Bending of cilia and flagella occurs when axonemal dynein molecules on one side of the axoneme produce force and move toward the microtubule (MT) minus end.
Shimaa A Abdellatef, Hisashi Tadakuma, Kangmin Yan, Takashi Fujiwara, Kodai Fukumoto, Yuichi Kondo, Hiroko Takazaki, Rofia Boudria, Takuo Yasunaga, Hideo Higuchi, Keiko Hirose   +10 more
doaj   +1 more source

State-of-the-Art Molecular Biophysics in Russia. [PDF]

Int J Mol Sci
Thirty years ago, scientists’ attention was focused on studying individual molecules, as well as their structure and function [...]
Galzitskaya OV.
europepmc   +3 more sources

Cells Best Paper Award 2015 Alexander E.

Cells, 2015
Cells has instituted a “Best Paper” award to recognize the most outstanding papers in the area of cell biology, molecular biology, and biophysics, published in Cells.
Alexander E. Kalyuzhny
doaj   +1 more source

Metabolomic profiling of ZrO2 nanoparticles in MC3T3‐E1 cells

IET Nanobiotechnology, 2021
The authors' previous study showed that zirconium oxide nanoparticles (ZrO2 NPs) induce toxic effects in MC3T3‐E1 cells; however, its toxicological mechanism is still unclear.
Mingfu Ye, Linhu Wang, Zhang Wu, Wenjun Liu   +3 more
doaj   +1 more source

Biophysical and flavonoid-binding studies of the G protein ectodomain of group A human respiratory syncytial virus

Heliyon, 2019
The human Respiratory Syncytial Virus (hRSV) is the major causative agent of lower respiratory tract diseases in infants, young children and elderly. The membrane protein G is embedded in the viral lipid envelope and plays an adhesion function of the ...
Vitor Brassolatti Machado, Jéssica Maróstica de Sá, Ana Karla Miranda Prado, Karina Alves de Toledo, Luis Octávio Regasini, Fátima Pereira de Souza, Ícaro Putinhon Caruso, Marcelo Andres Fossey   +7 more
doaj   +1 more source

Molecular Organization of Membranes: Where Biology Meets Biophysics [PDF]

, 2018
Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling.
Cebecauer, Marek, Holowka, David, Marek Cebecauer, David Holowka   +3 more
core   +1 more source

Protein cages as building blocks for superstructures

Engineering Biology, 2021
Proteins naturally self‐assemble to function. Protein cages result from the self‐assembly of multiple protein subunits that interact to form hollow symmetrical structures with functions that range from cargo storage to catalysis. Driven by self‐assembly,
Ruoxuan Sun, Sierin Lim
doaj   +1 more source

Expanding the scale of molecular biophysics [PDF]

Physical Biology, 2016
Here, I argue that some of the secrets of complex biological function rely on assemblies of many heterogeneous proteins that together enable sophisticated sensing and actuating processes. Evolution seems to delight in making these structures and in continually elaborating upon their capabilities.
openaire   +2 more sources