Results 41 to 50 of about 318,972 (299)
iScience, 2018 Summary: Cell membrane is the first medium from where a cell senses and responds to external stress stimuli. Exploring the tension changes in cell membrane will help us to understand intracellular force transmission.
Wang Li +8 more
doaj +1 more source
How far can stochastic and deterministic views be reconciled?
, 2012 In this short note, we try to provide the reader with a brief pedagogical account of some similarities and differences between stochastic and deterministic processes.
Bergé +7 more
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Molecular architecture of human polycomb repressive complex 2. [PDF]
, 2012 Polycomb Repressive Complex 2 (PRC2) is essential for gene silencing, establishing transcriptional repression of specific genes by tri-methylating Lysine 27 of histone H3, a process mediated by cofactors such as AEBP2.
Aebersold, Ruedi +5 more
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Discrete kinetic models for molecular motors: asymptotic velocity and gaussian fluctuations
, 2014 We consider random walks on quasi one dimensional lattices, as introduced in \cite{FS}. This mathematical setting covers a large class of discrete kinetic models for non-cooperative molecular motors on periodic tracks.
Faggionato, Alessandra +1 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A novel N-terminal extension in mitochondrial TRAP1 serves as a thermal regulator of chaperone activity. [PDF]
, 2014 Hsp90 is a conserved chaperone that facilitates protein homeostasis. Our crystal structure of the mitochondrial Hsp90, TRAP1, revealed an extension of the N-terminal β-strand previously shown to cross between protomers in the closed state. In this study,
Agard, David A +5 more
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Advances in Terahertz Biophysics and Chemistry
ResearchAs terahertz (THz) science and technology continue to advance, THz biophysics and chemistry have emerged as a pivotal interface, linking molecular-scale insights with transformative innovations in biological, physical, and chemical sciences.
Zhi Zhu +5 more
doaj +1 more source
Deciphering the Gene Regulatory Landscape Encoded in DNA Biophysical Features
iScience, 2019 Summary: Gene regulation in higher organisms involves a sophisticated interplay between genetic and epigenetic mechanisms. Despite advances, the logic in selective usage of certain genomic regions as regulatory elements remains unclear. Here we show that
Abhijeet Pataskar +5 more
doaj +1 more source
The effects of pH on the self-association of phycobiliprotein from Anacystis nidulans R₂ [PDF]
, 1988 Call number: LD2668 .T4 BICH 1988 V55Master of ScienceBiochemistry and Molecular Biophysics Interdepartmental ...
Vijayalakshmi, V.
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