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Supramolecular Aggregates: Hardness Plus Softness
The properties of supramolecular aggregates cross several disciplines, embracing the sciences of nature and joining theory, experiment, and application.
Lia Queiroz do Amaral
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Systems biology and cancer, [Editorial] [PDF]
The systems approach to complex biological problems has rapidly gained ground during the first decade of this century. There are several reasons for this development. An important one is that while the achievement of sequencing the complete human genome,
Maini, Philip +3 more
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Cells Best Paper Award 2015 Alexander E.
Cells has instituted a “Best Paper” award to recognize the most outstanding papers in the area of cell biology, molecular biology, and biophysics, published in Cells.
Alexander E. Kalyuzhny
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Metabolomic profiling of ZrO2 nanoparticles in MC3T3‐E1 cells
The authors' previous study showed that zirconium oxide nanoparticles (ZrO2 NPs) induce toxic effects in MC3T3‐E1 cells; however, its toxicological mechanism is still unclear.
Mingfu Ye +3 more
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A physical model of cell metabolism [PDF]
Cell metabolism is characterized by three fundamental energy demands: to sustain cell maintenance, to trigger aerobic fermentation and to achieve maximum metabolic rate.
Fernandez-de-Cossio-Diaz, Jorge +1 more
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The human Respiratory Syncytial Virus (hRSV) is the major causative agent of lower respiratory tract diseases in infants, young children and elderly. The membrane protein G is embedded in the viral lipid envelope and plays an adhesion function of the ...
Vitor Brassolatti Machado +7 more
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High-resolution and high-accuracy topographic and transcriptional maps of the nucleosome barrier. [PDF]
Nucleosomes represent mechanical and energetic barriers that RNA Polymerase II (Pol II) must overcome during transcription. A high-resolution description of the barrier topography, its modulation by epigenetic modifications, and their effects on Pol II ...
Brown, Aidan I +9 more
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Amyloid aggregates arise from either the partial or complete loss of the native protein structure or the inability of proteins to attain their native conformation. These aggregates have been linked to several diseases, including Alzheimer’s, Parkinson’s,
Gabriel Zazeri +4 more
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Mind-life continuity: a qualitative study of conscious experience [PDF]
There are two fundamental models to understanding the phenomenon of natural life. One is thecomputational model, which is based on the symbolic thinking paradigm. The other is the biologicalorganism model.
Hipólito, Inês, Martins, J.
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Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement. [PDF]
Eukaryotic DNA is packaged into nucleosome arrays, which are repositioned by chromatin remodeling complexes to control DNA accessibility. The Saccharomyces cerevisiae RSC (Remodeling the Structure of Chromatin) complex, a member of the SWI/SNF chromatin ...
Afonine +79 more
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