Results 81 to 90 of about 3,587,617 (298)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Thermofluidic chip containing virtual thermal wells

Engineering Biology, 2019
The authors describe a thermofluidic chip on which microscale islands of controlled temperature are formed within an open fluidic environment. The chip forms part of the authors’ technology for thermally controlled DNA synthesis, whereby the site ...
Andrew J. Ferguson, Matthew J. Hayes, Blair C. Kirkpatrick, Yen-chun Lin, Vijay Narayan, Albert Prak, Albert Prak   +6 more
doaj   +1 more source

Biophysics: Concepts and Fields [PDF]

There is an idiom that “biophysicist is who discusses about biology when meets physicist, talks about physics when meets biologist and says joke when meets another biophysicist”. This idiom points to multidisciplinary nature of biophysics but what really
امانی, مجتبی
core  

Look Beyond Plasma Membrane Biophysics: Revealing Considerable Variability of the Dipole Potential Between Plasma and Organelle Membranes of Living Cells

Due to the lack of measurement techniques suitable for examining compartments of intact, living cells, membrane biophysics is almost exclusively investigated in the plasma membrane despite the fact that its alterations in intracellular organelles may ...
Florina Zakany, Mate Szabo, Zoltan Varga, Kitti Kurtan, Peter Nagy, Bence Cs. Szabo, Gyorgy Panyi, Tamas Kovacs, Cs. Szabó, Bence, Kurtán, Kitti, Kovács, Tamás, Szabó, Máté, Panyi, György, Nagy, Péter, Varga, Zoltán, Zákány, Florina   +15 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Data model for biopart datasheets

Engineering Biology, 2018
This study introduces a new data model, based on the DICOM-SB (see glossary of terms for definition of acronyms) standard for synthetic biology, that is capable of describing/incorporating the data, metadata and ancillary information from detailed ...
Iñaki Sainz de Murieta, Matthieu Bultelle, Richard I. Kitney   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Unveiling islet heterogeneity using an automated microfluidic imaging system

Scientific Reports
Islets of Langerhans are a therapeutic target for diabetes and prediabetes. Measurements of therapeutic inhibitory or excitatory concentrations are often performed using large groups of islets, however, the population heterogeneity cannot be observed ...
James Thornham, Richard Bertram, Michael G. Roper   +2 more
doaj   +1 more source

Biophysics and Molecular Biology [PDF]

Nature, 1962
Molecular Biophysics By Richard B. Setlow and Ernest C. Pollard. (Addison-Wesley Series in the Life Sciences.) Pp. xiii + 545. (London: Pergamon Press, 1962.) 84s. net.
openaire   +1 more source

Fundamental Concepts in Biophysics

, 2009
HANDBOOK OF MODERN BIOPHYSICS Series Editor Thomas Jue, PhD Handbook of Modern Biophysics brings current biophysics topics into focus, so that biology, medical, engineering, mathematics, and physical-science students or researchers can learn fundamental ...
Jue, Thomas
core   +1 more source