Results 161 to 170 of about 225,633 (278)

The Emerging Role of the Molecular Chaperone Clusterin in Parkinson's Disease. [PDF]

Int J Mol Sci
Carini G, Mohammed S, Filippini A, Ramazzina I, Russo I.   +4 more
europepmc   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Targeting and dissociating HIF2α from the molecular chaperone Hsp70 triggers apoptosis in kidney cancer. [PDF]

Commun Med (Lond)
Heritz JA, Backe SJ, Pacherille A, Cayaban SJ, Basin MF, Smith B, Sager RA, Daneshvar M, Post DE, Woodford MR, Bourboulia D, Chisholm JD, Mollapour M, Bratslavsky G.   +13 more
europepmc   +1 more source

The Molecular Chaperone Mechanism of the C-Terminal Domain of Large-Size Subunit Catalases. [PDF]

Antioxidants (Basel), 2023
Nava-Ramírez T, Gutiérrez-Terrazas S, Hansberg W.   +2 more
europepmc   +1 more source

Immunometabolic and Spatiotemporal Control of Tissue‐Resident Memory T Cell Biology

Barrier Immunity, EarlyView.
Tissue‐resident memory T (TRM) cells in barrier tissues provide a frontline defense against invading pathogens. Immune (Signals 1–3) and nutrient (Signal 4) cues play an integral role in directing TRM formation and heterogeneity. The spatial and temporal organization of these signals establishes durable TRM cells across tissues, enabling diverse ...
Jana L. Raynor, Hongbo Chi
wiley   +1 more source

Molecular chaperone effects on recombinant yield and binding characteristics of an ABA-specific scFv in <i>Escherichia coli</i>. [PDF]

Front Bioeng Biotechnol
Chen S, Shan B, Luo Y, Mo G, Rasheed U, Lv L, Yang X, Lu Q.   +7 more
europepmc   +1 more source

The yeast molecular chaperone, Hsp104, influences transthyretin aggregate formation. [PDF]

Front Mol Neurosci, 2022
Knier AS, Davis EE, Buchholz HE, Dorweiler JE, Flannagan LE, Manogaran AL.   +5 more
europepmc   +1 more source

Mosaic activation of the zebrafish hsp70l heat shock promoter: Implications for interpreting transgenes

Developmental Dynamics, EarlyView.
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley   +1 more source

The molecular chaperone TRAP1 promotes translation of <i>Luc7I3</i> mRNA to enhance ovarian cancer cell proliferation. [PDF]

RNA
De Lella S, Pedalino L, Abaker MAA, Mignogna C, Cautiero R, Esposito F, Matassa DS, Avolio R.   +7 more
europepmc   +1 more source

Formation of Fibrils by the Periplasmic Molecular Chaperone HdeB from Escherichia coli. [PDF]

Int J Mol Sci, 2022
Nakata Y, Kitazaki Y, Kanaoka H, Shingen E, Uehara R, Hongo K, Kawata Y, Mizobata T.   +7 more
europepmc   +1 more source