Results 1 to 10 of about 754,256 (218)

Molecular Classification of Knee Osteoarthritis

Frontiers in Cell and Developmental Biology, 2021
Knee osteoarthritis (KOA) is the most common form of joint degeneration with increasing prevalence and incidence in recent decades. KOA is a molecular disorder characterized by the interplay of numerous molecules, a considerable number of which can be ...
Zhongyang Lv, Yannick Xiaofan Yang, Jiawei Li, Yuxiang Fei, Hu Guo, Ziying Sun, Jun Lu, Xingquan Xu, Qing Jiang, Shiro Ikegawa, Dongquan Shi   +10 more
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Beyond the WHO classification of meningioma: using molecular diagnostics to guide management

Advances in Clinical Neuroscience & Rehabilitation, 2023
Meningioma are the most common primary brain tumour. Classically, meningioma are phenotypically grouped using the World Health Organisation (WHO) classification system.
Abigail Clynch, George E Richardson, Mohammad A Mustafa, Conor S Gillespie, Nitika Rathi, Ali Bakhsh, Rasheed Zakaria, Abdurrahman I Islim, Christopher P Millward, Michael D Jenkinson   +9 more
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Systematic metabolic characterization of mental disorders reveals age‐related metabolic disturbances as potential risk factors for depression in older adults

MedComm, 2022
Mental disorders are associated with dysregulated metabolism, but comprehensive investigations of their metabolic similarities and differences and their clinical relevance are few.
Yu Liu, Wanyu Zhao, Ying Lu, Yunli Zhao, Yan Zhang, Miao Dai, Shan Hai, Ning Ge, Shuting Zhang, Mingjin Huang, Xiaohui Liu, Shuangqing Li, Jirong Yue, Peng Lei, Biao Dong, Lunzhi Dai, Birong Dong   +16 more
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Next-Generation Sequencing Reveals a Very Low Prevalence of Deleterious Mutations of Homologous Recombination Repair Genes and Homologous Recombination Deficiency in Ovarian Clear Cell Carcinoma

Frontiers in Oncology, 2022
Ovarian clear cell carcinoma (OCCC) is aggressive and drug-resistant. The prevalence of homologous recombination repair (HRR) gene mutations and homologous recombination deficiency (HRD) remains largely unknown.
Hangqi Liu, Zhiwen Zhang, Longyun Chen, Junyi Pang, Huanwen Wu, Zhiyong Liang   +5 more
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Utility of TP53 in Breast Carcinoma Immunophenotypes [PDF]

Journal of Clinical and Diagnostic Research, 2020
Breast cancer is a heterogeneous disease and has significant variability in presentation, treatment response, and prognosis. The management of carcinoma breast is currently based on immunophenotypes and Tumour Nodes Metastasis (TNM) staging. The aim of
Ria Jaggi, Samarth Shukla, Sourya Acharya, Sunita Vagha   +3 more
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Molecular classification of diffuse gliomas

Polish Journal of Pathology, 2020
In this study we assessed whether gliomas could be subdivided into different molecular subtypes by immunohistochemistry (IHC) reminiscent of those first described by Verhaak et al. in 2010 (classical, proneural, mesenchymal and neural). We also evaluated
Arvids Jakovlevs, Andrejs Vanags, Janis Gardovskis, Ilze Strumfa   +3 more
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ASSOCIATION OF RS2069502 CYCLIN-DEPENDENT KINASE 4 GENE WITH BREAST CANCER [PDF]

Euromediterranean Biomedical Journal, 2020
The goal of this project was to evaluate the association of candidate genetic variant rs2069502 of the CDK4 gene with breast cancer and the effect of variant genotypes on the serum concentration of CDK4 enzyme and consequently, on the occurrence of ...
Dalya Shakir Al-owaidi
doaj   +1 more source

Pre-treatment risk assessment of women with endometrial cancer: differences in outcomes of molecular and clinical classifications in the Slovenian patient cohort

Radiology and Oncology, 2021
The aim of this study was to evaluate changes in prognostic risk profiles of women with endometrial cancer by comparing the clinical risk assessment with the integrated molecular risk assessment profiling.
Knez Jure, Sobocan Monika, Belak Urska, Kavalar Rajko, Zupin Mateja, Büdefeld Tomaz, Potocnik Uros, Takac Iztok   +7 more
doaj   +1 more source

A novel pyroptosis risk model composed of NLRP6 effectively predicts the prognosis of hepatocellular carcinoma patients

Cancer Medicine, 2023
Background Pyroptosis is a unique inflammatory‐related cell death process, and inflammation is considered to be a key factor in hepatocellular carcinoma (HCC). However, the pyroptosis landscape in HCC has not been thoroughly studied.
Xin Gao, Wen‐Xin Wang, Xiao‐Lan Zhang   +2 more
doaj   +1 more source

Canine Mammary Cancer: State of the Art and Future Perspectives

Animals, 2023
Mammary cancer is the most frequently diagnosed neoplasia in women and non-spayed female dogs and is one of the leading causes of death in both species.
Eliza Vazquez, Yulia Lipovka, Alejandro Cervantes-Arias, Adriana Garibay-Escobar, Michelle M. Haby, Felisbina Luisa Queiroga, Carlos Velazquez   +6 more
doaj   +1 more source