Results 131 to 140 of about 472,091 (296)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Molecular Cloning and Functional Characterization of the Rat Analogue of Human Decay-Accelerating Factor (CD55) [PDF]

, 1998
Stewart J. Hinchliffe, O. Brad Spiller, Neil K. Rushmere, B. Paul Morgan   +3 more
openalex   +1 more source

Molecular Cloning of POEM [PDF]

Journal of Biological Chemistry, 2001
Naoko Morimura, Yoko Tezuka, Naoko Watanabe, Masafumi Yasuda, Seiji Miyatani, Nobumichi Hozumi, Ken-ichi Tezuka   +6 more
openaire   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Molecular Cloning and Functional Analysis of Holin and Endolysin From Escherichia Phage UE-M6 as Potential Antibacterial Agents. [PDF]

Microbiologyopen
Niaz H, Skurnik M, Adnan F.
europepmc   +1 more source

Isolation, Molecular Cloning and Expression of Human Interferon Gamma (IFN-γ) Gene in Escherichia coli [PDF]

, 2016
Saber Ali, Nadia M. Abdallah, Eman Abd El-Azeem, Okasha Hend, A Muheem, F Shakeel, M Jahangir, M Anwar, N Mallick, G Jain, M Warsi, F Ahmad, F Sorgeloos, M Kreit, P Hermant, C Lardinois, T Michiels, J Tan, R Ramanan, S Azaman, T Ling, M Shuhaimi, H Akhtar, S Akhtar, U Rahee, M Faheem, M Arshad, M Yameen, Najam Zaidi, R Khalilzadeh, A Shojaosadati, E Maghsoudi, Mohammadian-Mosaabadi, M Mohammadi, A Bahrami, N Maleksabet, Nassiri-Khalilli, M Ebrahimi, E Naderimanesh, A Byum, R Katial, D Sachanandani, C Pinney, M Liberman, P Chomczynski, N Sacchi, S Shuman, D Holmes, M Quigley, F Sanger, S Nicklen, A Coulson, S Altschul, L Thomas, A Alejandro, Z Jinghui, Z Zheng, M Webb, J David, D Smith, K Johnson, W Burnette, M Fathi-Roudsari, A Akhavian-Tehrani, N Maghsoudi, T Chen, Y Lin, Y Lee, N Yang, M Chan, M Tsujimoto, T Tarutani, K Ogawa, K Akashi, Y Okubo, N Higashi, S Bandyopadhyay, S Bharracharyya, M Roy, K Roy, A Zamani, S Sadeghian, J Tavakkol-Afshari, E Nasiri, K Bagheri, M Javaran, F Mahboudi, A Moeini, A Zebarjadi, M Kamionka, T Arakawa, Y Hsu, C Parker, P Lai, E Rinderknecht, B O'connor, H Rodriguez, V Babaeipour, S Abbas, K Rasoul   +99 more
openalex   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Molecular cloning and characterization of duck CD83 and its effect on H9N2 avian influenza virus replication. [PDF]

Poult Sci
Li H, Xin X, Yin Z, Dong C, Li F, Liu Y, Kong X, Wang L, Wang J, Yu F, Huo S.   +10 more
europepmc   +1 more source