Results 191 to 200 of about 766,908 (329)

N-terminal Huntingtin (Htt) phosphorylation is a molecular switch regulating Htt aggregation, helical conformation, internalization, and nuclear targeting [PDF]

, 2018
Sean M. DeGuire, Francesco Simone Ruggeri, Mohamed-Bilal Fares, Anass Chiki, Urszula Cendrowska, Giovanni Dietler, Hilal A. Lashuel   +6 more
openalex   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Tuning Excited-State Properties in Pyrrolo[3,2-<i>b</i>]pyrrole-Based Donor-Acceptor Emitters via Molecular Conformation and Conjugation Control. [PDF]

Molecules
Gan T, Su J, Li F, Li Q, Shi C.
europepmc   +1 more source

Effect of intramolecular hydrogen-bond formation on the molecular conformation of amino acids. [PDF]

Commun Chem, 2020
Giubertoni G, Sofronov OO, Bakker HJ.
europepmc   +1 more source

Design and Synthesis of Matrix Metalloproteinase Inhibitors Guided by Molecular Modeling. Picking the S₁Pocket Using Conformationally Constrained Inhibitors

, 2001
Stephen Hanessian, D. Mackay, Nicolas Moitessier   +2 more
openalex   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Monitoring the Molecular Conformation of Individual Amphotericin B Molecules in an Aggregated State by Raman Optical Activity. [PDF]

Anal Chem
Pajor K, Zając G, Fusè M, Mach-Liszka M, Arczewska M, Gagoś M, Onaka Y, Fujisawa T, Unno M, Baranska M, Machalska E.   +10 more
europepmc   +1 more source

Personal Draft of Studying Macroscopic Physical Properties as a Molecular Science: Molecular Dynamics and Internal Motional/Conformational Degrees of Freedom

, 2023
Kazuya Saito
openalex   +2 more sources

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

Insight into the stabilization mechanism of rice protein amyloid fibrils modification on soy protein isolate gels: Gel properties, microstructure, and molecular conformation. [PDF]

Food Chem X
Ma J, Wang L, Pan D, Wang K, Huo J, Ma X, Lu B, Yu X, Xiao Z.   +8 more
europepmc   +1 more source