Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
wiley +1 more source
EC-Conf: A ultra-fast diffusion model for molecular conformation generation with equivariant consistency. [PDF]
Fan Z, Yang Y, Xu M, Chen H.
europepmc +1 more source
EARTHMOVER-BASED MANIFOLD LEARNING FOR ANALYZING MOLECULAR CONFORMATION SPACES. [PDF]
Zelesko N +3 more
europepmc +1 more source
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li +10 more
wiley +1 more source
Octaethyl vs Tetrabenzo Functionalized Ru Porphyrins on Ag(111): Molecular Conformation, Self-Assembly and Electronic Structure. [PDF]
Meier D +15 more
europepmc +1 more source
Structural characterisation of molecular conformation and the incorporation of adatoms in an on-surface Ullmann-type reaction. [PDF]
Judd CJ +6 more
europepmc +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
COSMIC: Molecular Conformation Space Modeling in Internal Coordinates with an Adversarial Framework. [PDF]
Kuznetsov M +6 more
europepmc +1 more source

