Results 31 to 40 of about 4,764,380 (406)
Common DNA sequence variation influences 3-dimensional conformation of the human genome. [PDF]
, 2019 BACKGROUND:The 3-dimensional (3D) conformation of chromatin inside the nucleus is integral to a variety of nuclear processes including transcriptional regulation, DNA replication, and DNA damage repair.
Chiou, Joshua +12 more
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Butane-1,4-diyl bis(chloroacetate) [PDF]
, 2020 The title compound, C8H12Cl2O4, lies about an inversion centre. The molecular conformation is characterized by a tgtgt conformation for the butanedioxy moiety and a trans conformation for the ClCH2ÐC( O)O bond.
Font Bardia, Ma. Mercedes +3 more
core +1 more source
On the dynamics of molecular conformation [PDF]
Proceedings of the National Academy of Sciences, 2006 Understanding the mechanism of fast transitions between conformed states of large biomolecules is central to reconciling the dichotomy between the relatively high speed of metabolic processes and slow (random-walk based) estimates on the speed of biomolecular processes.
openaire +2 more sources
A kernel-based approach to molecular conformation analysis [PDF]
Journal of Chemical Physics, 2018 We present a novel machine learning approach to understand conformation dynamics of biomolecules. The approach combines kernel-based techniques that are popular in the machine learning community with transfer operator theory for analyzing dynamical ...
Stefan Klus +3 more
semanticscholar +1 more source
Crystal structure of 2-benzoylamino-N′-(4-hydroxybenzylidene)-3-(thiophen-2-yl)prop-2-enohydrazide
Acta Crystallographica Section E: Crystallographic Communications, 2016 In the title compound, C21H17N3O3S, the non-H atoms, apart from those in the benzoyl group, are almost coplanar (r.m.s. deviation = 0.049 Å) and the benzoyl group is almost orthogonal to the plane of the rest of the molecule [dihedral angle = 80.34 (6)°].
Karanth N. Subbulakshmi +5 more
doaj +1 more source
Molecular conformation of destruxin A
Tetrahedron Letters, 1989 Abstract The peptide backbone conformation of destruxin A in CDCl3, as studied by NOESY, closely resembles its crystal conformation which was deduced by a single crystal x-ray analysis.
Gupta, Sandeep +4 more
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Acta Crystallographica Section E: Crystallographic Communications, 2015 In the molecules of the title compounds, (2E)-1-(3-bromo-thiophen-2-yl)-3-(2-methoxyphenyl)prop-2-en-1-one, C14H11BrO2S, (I), which crystallizes in the space group P-1 with four independent molecules in the asymmetric unit (Z′ = 8), and (2E)-1-(3 ...
Vasant S. Naik +5 more
doaj +1 more source
Frontiers in Genetics, 2021 Circular RNA (circRNA) is a novel regulatory non-coding RNA and participates in diverse physiological and pathological processes. However, the structures and molecular mechanisms of circRNAs remain unclear.
Handong Sun +14 more
doaj +1 more source
NMR analysis of the dynamic exchange of the NS2B cofactor between open and closed conformations of the West Nile Virus NS2B-NS3 protease [PDF]
, 2015 BACKGROUND The two-component NS2B-NS3 proteases of West Nile and dengue viruses are essential for viral replication and established targets for drug development.
Lim, Siew P. +5 more
core +1 more source
Geometrical eigen-subspace framework based molecular conformation representation for efficient structure recognition and comparison. [PDF]
Journal of Chemical Physics, 2017 We have developed an extended distance matrix approach to study the molecular geometric configuration through spectral decomposition. It is shown that the positions of all atoms in the eigen-space can be specified precisely by their eigen-coordinates ...
Xiaotian Li, Xiao-Bao Yang, Yu-Jun Zhao
semanticscholar +1 more source