Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
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Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming [PDF]
BACKGROUND: Although chronic morbidity in humans from soil transmitted helminth (STH) infections can be reduced by anthelmintic treatment, inconsistent diagnostic tools make it difficult to reliably measure the impact of deworming programs and often miss
A Ebrahim +75 more
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Use of genetic markers for the detection of off-types for DUS phenotypic traits in the inbreeding crop, barley [PDF]
Detection of crop off-types is of interest for multiple uses, including the assessment of uniformity for new plant variety applications during distinctness, uniformity and stability (DUS) testing for the awarding of plant breeders’ rights (PBR). Here,
Cockram, James +4 more
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Advances in Microfluidics and Lab-on-a-Chip Technologies
Advances in molecular biology are enabling rapid and efficient analyses for effective intervention in domains such as biology research, infectious disease management, food safety, and biodefense.
Abate +161 more
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Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari +118 more
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Era of Molecular Diagnostics Techniques before and after the COVID-19 Pandemic
Despite the growth of molecular diagnosis from the era of Hippocrates, the emergence of COVID-19 is still remarkable. The previously used molecular techniques were not rapid enough to screen a vast population at home, in offices, and in hospitals ...
Ahmad M. Alamri +2 more
doaj +1 more source
Biomarkers in solid organ transplantation: establishing personalized transplantation medicine. [PDF]
Technological advances in molecular and in silico research have enabled significant progress towards personalized transplantation medicine. It is now possible to conduct comprehensive biomarker development studies of transplant organ pathologies ...
Khatri, Purvesh +3 more
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Molecular Diagnostic Techniques of Infectious Diseases
Recent advancements in molecular techniques such as real-time PCR, isothermal amplification, next-generation sequencing, metagenomics, microarray, and CRISPR-based infectious disease diagnostics have significantly evolved and improved over the past ...
Michael Baclig
doaj +1 more source
Extrapulmonary infections with Legionella species are rare, but important to acknowledge. We report a case of infective endocarditis (IE) with Legionella bozemanae in a 66-year-old immunocompetent man with an aortic homograft.
Mai Sasaki Aanensen Fraz +10 more
doaj +1 more source
Diagnostic Techniques: Serological and Molecular Approaches☆
Virus laboratory diagnostics has an increasingly important role in modern patient care. Virological methods are needed to investigate the etiology of acute viral infection or the reactivation of a latent infection, as well as to follow virus load in antiviral treatments.
Vainionpää, R. +2 more
openaire +1 more source

