Results 1 to 10 of about 680,341 (256)

Molecular Diagnostics [PDF]

open access: yesJournal of the American Academy of Orthopaedic Surgeons, 2015
Orthopaedic infections are complex conditions that require immediate diagnosis and accurate identification of the causative organisms to facilitate appropriate management. Conventional methodologies for diagnosis of these infections sometimes lack accuracy or sufficient rapidity. Molecular diagnostics is an emerging area of bench-to-bedside research in
Hyonmin, Choe   +4 more
  +8 more sources

Beyond the WHO classification of meningioma: using molecular diagnostics to guide management

open access: yesAdvances in Clinical Neuroscience & Rehabilitation, 2023
Meningioma are the most common primary brain tumour. Classically, meningioma are phenotypically grouped using the World Health Organisation (WHO) classification system.
Abigail Clynch   +9 more
doaj   +1 more source

Clinical significance of HRAS and KRAS genes expression in patients with non–small-cell lung cancer - preliminary findings

open access: yesBMC Cancer, 2021
Background The RAS family protooncogenes, including KRAS, NRAS and HRAS, encode proteins responsible for the regulation of growth, differentiation and survival of many cell types.
Milena Pązik   +5 more
doaj   +1 more source

Differential Expression of AP-2 Transcription Factors Family in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma—A Bioinformatics Study

open access: yesCells, 2023
Members of the activator protein 2 (AP-2) transcription factor (TF) family are known to play a role in both physiological processes and cancer development. The family comprises five DNA-binding proteins encoded by the TFAP2A to TFAP2E genes.
Dagmara Szmajda-Krygier   +7 more
doaj   +1 more source

Detection of BRAF V600E in Fine-Needle Aspiration Samples of Thyroid Nodules by Droplet Digital PCR

open access: yesInternational Journal of Endocrinology, 2022
Background. BRAF exon 15 p.V600E (BRAF V600E) mutation has been established as an important molecular marker for papillary thyroid carcinoma diagnosis by ultrasound-guided fine-needle aspiration biopsy (FNAB).
Sang-Yu Lu   +14 more
doaj   +1 more source

Colorful Molecular Diagnostics [PDF]

open access: yesClinical Chemistry, 2012
Most diagnostic assays used daily in clinical laboratories are based on identifying and quantifying the presence of specific molecules that serve as markers of pathologic conditions and physiological status; however, these molecules are neither visualized nor counted directly.
Kapanidis, A, Crawford, R
openaire   +2 more sources

Assessment of the TGFB1 gene expression and methylation status of the promoter region in patients with colorectal cancer

open access: yesScientific Reports, 2022
The aim of this study was to evaluate the expression of the TGFB1 gene encoding the TGF-β1 cytokine in 64 patients, and then to compare it with clinico-pathological features.
Damian Wodziński   +5 more
doaj   +1 more source

Molecular diagnostic techniques [PDF]

open access: yesMedicine, 2009
Clinical microbiology laboratories increasingly rely on molecular diagnostic techniques. The various formats of nucleic acid amplification are the most frequently used molecular tests in the diagnosis of infectious diseases. In many clinical settings, polymerase chain reaction (PCR) is clearly the method of choice due to its exquisite sensitivity and ...
Kurkela, Satu, Brown, David W.G.
openaire   +2 more sources

Home - About - Disclaimer - Privacy