Results 21 to 30 of about 680,341 (256)

Benefit of everolimus as a monotherapy for a refractory breast cancer patient bearing multiple genetic mutations in the PI3K/AKT/mTOR signaling pathway

open access: yesCancer Biology & Medicine, 2018
A postmenopausal patient with a diagnosis of estrogen receptor (ER) (+), progesterone receptor (PR) (+), and human epidermal growth factor receptor-2 (HER2) (-) breast cancer was reported.
Yehui Shi   +8 more
doaj   +1 more source

HCN to HCO^+ Millimeter Line Diagnostics of AGN Molecular Torus I : Radiative Transfer Modeling [PDF]

open access: yes, 2007
We explore millimeter line diagnostics of an obscuring molecular torus modeled by a hydrodynamic simulation with three-dimensional nonLTE radiative transfer calculations.
Aalto S.   +7 more
core   +1 more source

Comprehensive Analysis of the Expression and Clinical Significance of RAS Family Members in Non-Small Cell Lung Cancer Based on Bioinformatics Data and the A549 Cell Line Model

open access: yesApplied Sciences, 2022
Lung cancer is the second most frequent worldwide diagnosed cancer. Mutations in the RAS genes family are among the most common oncogenic alterations occurring in non-small cell lung cancer (NSCLC). Many treatment options against KRAS mutations have been
Milena Pązik   +4 more
doaj   +1 more source

Molecular Diagnostic Techniques

open access: yesMedicine, 2001
Molecular diagnostic techniques will continue to transform clinical microbiology. They provide more rapid and sensitive testing that impacts directly on clinical management of infected patients. Molecular diagnostic tests arose from the need to detect micro-organisms that are slow or difficult to grow, or that are present in only small numbers. Nucleic
Fawley, Warren N, Wilcox, Mark H
openaire   +2 more sources

Non-coding RNAs in saliva: emerging biomarkers for molecular diagnostics. [PDF]

open access: yes, 2015
Saliva is a complex body fluid that comprises secretions from the major and minor salivary glands, which are extensively supplied by blood. Therefore, molecules such as proteins, DNA, RNA, etc., present in plasma could be also present in saliva.
Majem, Blanca   +3 more
core   +4 more sources

Molecular Diagnostics [PDF]

open access: yesBioMed Research International, 2013
Akanchha Kesari   +3 more
  +7 more sources

Molecular diagnostics in tuberculosis [PDF]

open access: yes, 2005
Molecular diagnostics in tuberculosis has enabled rapid detection of Mycobacterium tuberculosis complex in clinical specimens, identification of mycobacterial species, detection of drug resistance, and typing for epidemiological investigation.
Cheng, VCC, Yew, WW, Yuen, KY
core   +1 more source

Diagnostic applications of next generation sequencing: working towards quality standards [PDF]

open access: yes, 2012
Over the past 6 years, next generation sequencing (NGS) has been established as a valuable high-throughput method for research in molecular genetics and has successfully been employed in the identification of rare and common genetic variations. All major
Adey   +42 more
core   +1 more source

The H II Region/PDR Connection: Self-Consistent Calculations of Physical Conditions in Star-Forming Regions [PDF]

open access: yes, 2005
We have performed a series of calculations designed to reproduce infrared diagnostics used to determine physical conditions in star forming regions. We self-consistently calculate the thermal and chemical structure of an H II region and photodissociation
Abel, N. P.   +3 more
core   +3 more sources

Molecular Lines as Diagnostics of High Redshift Objects [PDF]

open access: yes, 1997
Models are presented for CO rotational line emission by high redshift starburst galaxies. The influence of the cosmic microwave background on the thermal balance and the level populations of atomic and molecular species is explicitly included ...
Hogerheijde M. R.   +4 more
core   +3 more sources

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