Results 211 to 220 of about 732,309 (269)

Molecular evolution of mosaic chromosome 18 copy-number alterations from gametes to hepatoblastoma. [PDF]

JHEP Rep
Cendres E, Cornet M, Gautier Z, Pire A, Urvoy N, Morcrette G, Simaga F, Guimier A, Chardot C, Capito C, Schleiermacher G, Masliah-Planchon J, Pierron G, Taddei I, Stoppa-Lyonnet D, Zucman-Rossi J, Romana S, Aerts I, Hirsch TZ.   +18 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

A Prolonged Norovirus Infection and the Molecular Evolution of Human Norovirus Within-Host in a Child with Burkitt Lymphoma. [PDF]

Viruses
Jia L, De R, Li Z, Han Z, Liu L, Dong H, Feng S, Liu R, Zhao L.   +8 more
europepmc   +1 more source

Functional consistency and molecular evolution: a comprehensive characterization of primary endometrial cancer-associated fibroblasts during in vitro expansion. [PDF]

J Transl Med
Bao L, Wang P, Wang D, Li X, Zhang H, Wan X, Yuan R, Xie N, Lei L, Cheng Q, Lei X, Cao X, Dai H, Zheng T, Jiang H.   +14 more
europepmc   +1 more source

Molecular evolution and mechanisms underlying extremely high-level carbapenem resistance in the emerging CRPA clone ST1976. [PDF]

BMC Microbiol
Gong Y, Shao Y, Shen Y, Li P, Zhao X, Tian X, Li R, Qin S.   +7 more
europepmc   +1 more source

Molecular evolution and diversity of isomerase-reductase clusters involved in the bacterial metabolism of glycosaminoglycans. [PDF]

mSphere
Nishimura Y, Okumura K, Oiki S, Ogura K, Hashimoto W.   +4 more
europepmc   +1 more source

Molecular Evolution of the Chikungunya Virus <i>E1</i> Gene in Saudi Arabia: Predominance of Purifying Selection and ECSA/IOL Lineage Circulation. [PDF]

Viruses
Farrag MA.
europepmc   +1 more source

Molecular evolution of starch structure and sugar supply dynamics during the initial fermentation stages of Jiangxiangxing Baijiu. [PDF]

Food Chem X
Zhang B, Yang Y, Ni D, Xu Y, Zhuang C, Kong X, Yang F.   +6 more
europepmc   +1 more source