Results 211 to 220 of about 9,026,651 (342)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Molecular Evolution and Epidemiological Dynamics of Foot-and-Mouth Disease Virus O/ME-SA/Ind-2001e Circulating in East Java, Indonesia, in 2022-2025. [PDF]

Vet Med Int
Dinana Z, Rahmahani J, Suwarno, Hamid IS, Al-Arif MA, Yunus M, Tyasningsih W, Ihsan IS, Maharani AT, Maulana FK, Said NS, Fahrodi DU, Rantam FA.   +12 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Experimental and Computational Simulation of the Prebiotic Peptide Bond Formation Driven by Wet-Dry Cycles and Gamma Ionizing Radiation: An Insight into Molecular Evolution. [PDF]

J Mol Evol
Fonseca-González E, Fuentes-Carreon CA, Heredia-Barbero A.   +2 more
europepmc   +1 more source

Plastid phylogenomics and molecular evolution of Alismatales

Cladistics, 2016
T. G. Ross, Craig F. Barrett, Marybel Soto Gomez, V. Lam, C. L. Henriquez, D. Les, Jerrold I. Davis, Argelia Cuenca, G. Petersen, O. Seberg, Marcela Thadeo, T. Givnish, J. Conran, D. Stevenson, S. Graham   +14 more
semanticscholar   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Molecular Evolution and Epidemiology of Norovirus GII.4 Viruses in the United States. [PDF]

J Infect Dis
Barclay L, Montmayeur AM, Cannon JL, Mallory ML, Reyes YI, Wall H, Baric RS, Lindesmith LC, Vinjé J, Chhabra P.   +9 more
europepmc   +1 more source

Structural design and molecular evolution of a cytokine receptor superfamily.

Proceedings of the National Academy of Sciences of the United States of America, 1990
J. Bazan
semanticscholar   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Exogenous amdoparvoviruses (Parvoviridae) in arvicoline voles: the molecular evolution and ecology of a novel host-viral association. [PDF]

PLoS Pathog
Jackson JA, Begon M, Bradley JE, Friberg IM, Hyde S, Wanelik KM, Paterson S.   +6 more
europepmc   +1 more source