Results 221 to 230 of about 732,309 (269)

The emergence and molecular evolution of H5N1 influenza viruses in United States dairy cattle

Pekar JE, Gangavarapu K, Crespo-Bellido A, Peacock TP, Wertheim JO, Dudas G, Joy JB, Chand M, Débarre F, Gangavarapu P, Goldhill DH, Groves N, Ji X, Malpica Serrano L, Moncla L, Rasmussen AL, Ruis C, Venkatesh D, Kraemer MUG, Pybus OG, Andersen KG, Suchard MA, Nelson MI, Lemey P, Worobey M, Rambaut A.   +25 more
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Molecular Evolution of Aphthoviruses

Virus Genes, 1995
Aphthoviruses are an important group of animal pathogens. A combination of genetic and structural studies has revealed one of the main principles governing their evolution: severe limitations to variation imposed by functional and structural constraints, in conjunction with high mutation and recombination rates operating during genome replication ...
Domingo, Esteban, Mateu, Mauricio G., Escarmís, Cristina, Martínez-Salas, Encarnación, Andreu, David, Giralt, Ernest, Verdaguer, Núria, Fita, Ignacio   +7 more
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The Molecular Evolution of Trypanosomes

Parasitology Today, 1999
The absence of a fossil record has meant that the evolution of protozoa has remained largely a matter for speculation. Recent advances in molecular biology and phylogenetic analysis, however, are allowing the 'history written in the genes' to be interpreted. Here, Jamie Stevens and Wendy Gibson review progress in reconstruction of trypanosome phylogeny
Stevens, JR, Gibson, WC
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Molecular Evolution of Adenoviruses

2003
New advances in the field of genetic characterization of adenoviruses originating from different animal species are summarized. Variations seen in the host range and specificity, pathogenicity, genomic arrangement or gene complement are much wider than expected based on previous studies of human adenoviruses.
M, Benkö, B, Harrach
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Directed Molecular Evolution

Origins of life and evolution of the biosphere, 1999
We propose the existence of a relationship of stereochemical complementarity between gene sequences that code for interacting components: nucleic acid-nucleic acid, protein-protein and protein-nucleic acid. Such a relationship would impose evolutionary constraints on the DNA sequences themselves, thus retaining these sequences and governing the ...
L F, Harris, M R, Sullivan, D L, Hatfield   +2 more
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On the rate of molecular evolution

Journal of Molecular Evolution, 1971
There are at least two outstanding features that characterize the rate of evolution at the molecular level as compared with that at the phenotypic level. They are; (1) remarkable uniformity for each molecule, and (2) very high overall rate when extrapolated to the whole DNA content.
M, Kimura, T, Ota
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Molecular Evolution of Catalysis

Journal of Theoretical Biology, 2000
In this paper, we consider the evolutionary dynamics of catalytically active species with a distinct genotype-phenotype relationship. Folding landscapes of RNA molecules serve as a paradigm for this relationship with essential neutral properties. The landscape itself is partitioned by phenotypes (realized as RNA secondary structures). To each genotype (
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The molecular evolution of trypanosomatidae

2001
In the absence of a fossil record, theories relating to the evolution of protozoa have, for most of the twentieth century, been based on morphological and life cycle data despite their known limitations. However, recent advances in molecular methodology, notably the wide availability of accurate, automated DNA sequencing, have made it possible to ...
J R, Stevens, H A, Noyes, C J, Schofield, W, Gibson   +3 more
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Molecular insights into evolution

Artificial Life and Robotics, 1999
The evolution of ribonucleic acid (RNA) molecules in the test tube provides a possible way to study evolutionary optimization and adaptation to the environment on time scales accessible to human observers. Diversity of genotypes, however, is prohibitive for a complete experimental recording of the process at the molecular level.
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