Results 51 to 60 of about 134,922 (143)
The Genetic Code as a Chronicle of Early Events in the Origin of Life [PDF]
arXiv, 1998 Molecular evidence regarding the genetic code has been examined and the findings on the nature of the early events responsible for the amino acid distribution in the code are reported.
arxiv
Genetic Recombination as a Chemical Reaction Network [PDF]
arXiv, 2015 The process of genetic recombination can be seen as a chemical reaction network with mass-action kinetics. We review the known results on existence, uniqueness, and global stability of an equilibrium in every compatibility class and for all rate constants, from both the population genetics and the reaction networks point of view.
arxiv
Schlafen-5 inhibits LINE-1 retrotransposition
iScience, 2023 Summary: Long interspersed element 1 (LINE-1) is the only currently known active autonomous transposon in humans, and its retrotransposition may cause deleterious effects on the structure and function of host cell genomes and result in sporadic genetic ...
Jiwei Ding +24 more
doaj
Disentangling genetic and environmental risk factors for individual diseases from multiplex comorbidity networks [PDF]
arXiv, 2016 Most disorders are caused by a combination of multiple genetic and/or environmental factors. If two diseases are caused by the same molecular mechanism, they tend to co-occur in patients. Here we provide a quantitative method to disentangle how much genetic or environmental risk factors contribute to the pathogenesis of 358 individual diseases ...
arxiv
The Hippo pathway uses different machinery to control cell fate and organ size
iScience, 2021 Summary: The Hippo pathway is a conserved signaling network that regulates organ growth and cell fate. One such cell fate decision is that of R8 photoreceptor cells in the Drosophila eye, where Hippo specifies whether cells sense blue or green light.
Jonathan M. Pojer +4 more
doaj
YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1
iScience, 2021 Summary: Ventilation is dependent upon pulmonary alveoli lined by two major epithelial cell types, alveolar type-1 (AT1) and 2 (AT2) cells. AT1 cells mediate gas exchange while AT2 cells synthesize and secrete pulmonary surfactants and serve as ...
Jason J. Gokey +6 more
doaj
Genetic and functional analysis reveals TENM4 contributes to schizophrenia
iScience, 2021 Summary: TENM4, encoding a member of the teneurin protein family, is a risk gene shared by many types of mental diseases and is implicated in neuronal plasticity and signaling.
Xin Yi +12 more
doaj
MOLECULAR GENETICS FUNDAMENTALS AND WOMEN DISEASES GENЕTIC RISK FACTORS
Медицинский вестник Юга России, 2016 Exponential data quantity growth in the field of molecular genetics and genetic terminology growing list can easily confuse the doctor who doesn’t have special preparation.
E. A. Maylyan, D. E. Maylyan
doaj +1 more source
Molecular genetics related to non-Hodgkin lymphoma
Open Life Sciences, 2016 Non-Hodgkin lymphoma (NHL) is a serious disease, with a high proportion of mortality. Molecular genetic abnormalities are very common in NHL, but specific characterization in accordance to molecular genetics for lymphoma subtypes is not yet completed ...
Guo Ming, Mao Xianglin, Ding Xiaoqing
doaj +1 more source
Molecular genetics of Dupuytren’s contracture
EFORT Open ReviewsDupuytren’s contracture (DC) is a fibroproliferative disorder of the palmar fascia characterised by the digits’ flexion contractures and is associated with abnormal build-up of type III collagen.
Shankar Aissvarya +3 more
doaj +1 more source