Results 51 to 60 of about 3,947,894 (203)

Hydrogen Inhalation Reduces Lung Inflammation and Blood Pressure in the Experimental Model of Pulmonary Hypertension in Rats

Biomedicines, 2023
Hydrogen has been shown to exhibit selective antioxidant properties against hydroxyl radicals, and exerts antioxidant and anti-inflammatory effects.
Tatyana Kuropatkina, Dmitrii Atiakshin, Fedor Sychev, Marina Artemieva, Tatyana Samoilenko, Olga Gerasimova, Viktoriya Shishkina, Khaydar Gufranov, Natalia Medvedeva, Tyler W. LeBaron, Oleg Medvedev   +10 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Hydrogen medicine: A rising star in gas medicine

Traditional Medicine and Modern Medicine, 2020
Gas medicine, including O2, NO, H2S, CO, CH4, has played important roles in prevention and treatment of diseases for a long time. Molecular hydrogen (H2), the smallest diatomic molecule in nature, has become a rising star in gas medicine in the past ...
Dongyue Du, Lin Zhao, Meihua Shen, Mami Noda, Shucun Qin, Jiangang Long, Xuejun Sun, Jiankang Liu   +7 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Protective Effect of Molecular Hydrogen Following Different Routes of Administration on D-Galactose-Induced Aging Mice

Journal of Inflammation Research, 2021
Boyan Liu,1– 3,* Yunbo Xie,2,4,* Jun Chen,4 Junli Xue,1– 3 Xiaoyi Zhang,2 Min Zhao,2 Xiubin Jia,2 Yiwei Wang,4 Shucun Qin1,2 1The Second Affiliated Hospital of Shandong First Medical University, Tai’an, 271000, People’s Republic of China ...
Liu B, Xie Y, Chen J, Xue J, Zhang X, Zhao M, Jia X, Wang Y, Qin S   +8 more
doaj  

Understanding Hydrogen: Lessons to Be Learned from Physical Interactions between the Inert Gases and the Globin Superfamily

Oxygen, 2022
Hydrogen gas (molecular hydrogen, H2) has significant effects in a range of organisms, from plants to humans. Many inert gases have been reported to have similar effects, and such responses may be most pronounced when cells are stressed.
John T. Hancock, Grace Russell, Tim J. Craig, Jennifer May, H. Ruth Morse, Jonathan S. Stamler   +5 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Molecular Hydrogen and Extracorporeal Gas Exchange: A Match Made in Heaven? An In Vitro Pilot Study

Biomedicines
Extracorporeal circulation (ECC) is frequently implemented in a vast array of modalities such as hemodialysis, cardiopulmonary bypass, extracorporeal membrane oxygenation (ECMO), and others.
Foivos Leonidas Mouzakis, Flutura Hima, Ali Kashefi, Johannes Greven, Lothar Rink, Emiel P. C. van der Vorst, Joachim Jankowski, Khosrow Mottaghy, Jan Spillner   +8 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Water Decomposition Occurring During Laser Breakdown of Aqueous Solutions Containing Individual Gold, Zirconium, Molybdenum, Iron or Nickel Nanoparticles

Frontiers in Physics, 2020
Generation rates of hydrogen peroxide (H2O2), hydroxyl radicals (•OH), molecular hydrogen (H2), and molecular oxygen (O2) forming during the optical breakdown of aqueous colloidal solutions containing Au, Mo, Zr, Fe, and Ni nanoparticles have been ...
Ilya V. Baimler, Andrey B. Lisitsyn, Sergey V. Gudkov   +2 more
doaj   +1 more source