Results 111 to 120 of about 1,769,037 (315)

Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model

open access: yesNature Communications, 2020
Better tumor models are needed for the neuroendocrine subtype of castration resistant prostate cancer (CRPC-NE). Here, the authors develop patient-derived model from circulating tumor cells of a CRPC-NE patient, and provide insights on the sequential ...
Vincent Faugeroux   +21 more
doaj   +1 more source

A molecular toolbox for xanthophyll genes in wheat

open access: yes, 2008
The biological accumulation of xanthophyll compounds responsible for differences in yellow colouration of the wheat endosperm is of considerable commercial interest for specific end use products.
Ryan, K.   +8 more
core  

Molecular identification of prey in predator diets [PDF]

open access: yesMolecular Ecology, 2002
AbstractIn many situations prey choice by predators in the field cannot be established or quantified using direct observation. The remains of some prey may be visually identified in the guts and faeces of predators but not all predators ingest such hard remains and even those that do consume them may also ingest soft‐bodies prey that leave no ...
openaire   +2 more sources

Molecular characterization and biomarker identification in colorectal cancer: Toward realization of the precision medicine dream

open access: yes, 2018
Gaurav Goel Division of Hematology-Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Abstract: Colorectal cancer (CRC) is a major public health problem, both in the USA and globally.
Goel G
core  

Conventional Biochemical Identification vs. Molecular Identification.

open access: yes, 2015
*Mycobacteria spp.: mycobacteria species that failed to be further identified by conventional biochemical methods.Conventional Biochemical Identification vs. Molecular Identification.
Fung-Rong Hu (223287)   +3 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Seed dormancy and seed longevity: from genetic variation to gene identification

open access: yes, 2014
Seed dormancy and seed longevity are the most important survival traits in the soil seed bank. Both traits are induced during seed maturation and evolved to assure seed survival during environmental conditions that cannot support the regular course of ...
Nguyen, T.P.   +2 more
core  

The mechanism of parvalbumin interneurons regulating glutamatergic neurons involvement in stress induced anxiety in the basolateral amygdala of male mice

open access: yesScientific Reports
Modern life’s fast-paced and the unexpected conditions contribute to escalating stress levels, often leading to anxiety disorders and posing significant challenges to physical and mental health. In judicial practice, the parties often suffer from anxiety
Xiaorui Su   +9 more
doaj   +1 more source

Endogenous and Exogenous Small RNA Signatures as Novel Tools for Postmortem Interval Determination

open access: yesBiomolecules
Background: Accurate estimation of the postmortem interval (PMI), the time elapsed between death and body discovery, is a critical challenge in forensic science due to the complex interplay of factors affecting decomposition. Traditional methods based on
Yafei Wang   +9 more
doaj   +1 more source

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