Results 81 to 90 of about 11,582,729 (334)

Organic Semiconducting Agents for Deep‐Tissue Molecular Imaging: Second Near‐Infrared Fluorescence, Self‐Luminescence, and Photoacoustics

open access: yesAdvances in Materials, 2018
Optical imaging has played a pivotal role in biology and medicine, but it faces challenges of relatively low tissue penetration and poor signal‐to‐background ratio due to light scattering and tissue autofluorescence. To overcome these issues, second near‐
Qingqing Miao, Kanyi Pu
semanticscholar   +1 more source

Accurate image derived input function in [18F]SynVesT-1 mouse studies using isoflurane and ketamine/xylazine anesthesia

open access: yesEJNMMI Physics, 2023
Background Kinetic modeling in positron emission tomography (PET) requires measurement of the tracer plasma activity in the absence of a suitable reference region.
Alan Miranda   +3 more
doaj   +1 more source

CCT4 promotes tunneling nanotube formation

open access: yesFEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto   +3 more
wiley   +1 more source

Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. [PDF]

open access: yes, 2014
Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate.
Arce, Fernando Teran   +5 more
core   +2 more sources

Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation

open access: yesScience Translational Medicine, 2019
Molecular imaging could fulfill unmet clinical needs for diagnosing and monitoring bacterial infections, if translational barriers are addressed. Clinical diagnostic tools requiring direct sample testing cannot be applied to infections deep within the ...
A. Ordonez   +7 more
semanticscholar   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Chemical Self Assembly of Graphene Sheets [PDF]

open access: yes, 2009
Chemically derived graphene sheets were found to self-assemble onto patterned gold structures via electrostatic interactions between noncovalent functional groups on GS and gold. This afforded regular arrays of single graphene sheets on large substrates,
Dai, Hongjie   +3 more
core   +1 more source

Molecular Imaging in the Second Near‐Infrared Window

open access: yesAdvanced Functional Materials, 2019
In the past decade, noticeable progress has been achieved regarding fluorescence imaging in the second near‐infrared (NIR‐II) window. Fluorescence imaging in the NIR‐II window demonstrates superiorities of deep tissue penetration and high spatial and ...
Hao Wan, Haotian Du, Feifei Wang, H. Dai
semanticscholar   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

Synthesis of Fluorine-18 Functionalized Nanoparticles for use as in vivo Molecular Imaging Agents [PDF]

open access: yes, 2008
Nanoparticles containing fluorine-18 were prepared from block copolymers made by ring opening metathesis polymerization (ROMP). Using the fast initiating ruthenium metathesis catalyst (H_2IMes)(pyr)_2(Cl)_2Ru=CHPh, low polydispersity amphiphilic block ...
, X. K.   +54 more
core   +3 more sources

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