Results 91 to 100 of about 12,554,924 (329)
Viruses, 2022 The rapid emergence of antibiotic resistance is of major concern globally. Among the most worrying pathogenic bacteria are vancomycin-resistant enterococci. Phage therapy is a highly promising method for controlling enterococcal infections. In this study,
Pavel V. Tkachev +6 more
doaj +1 more source
Efficient atomic self-interaction correction scheme for non-equilibrium quantum transport
, 2006 Density functional theory calculations of electronic transport based on local exchange and correlation functionals contain self-interaction errors. These originate from the interaction of an electron with the potential generated by itself and may be ...
A. R. Rocha +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
MINERVA—a platform for visualization and curation of molecular interaction networks
npj Systems Biology and Applications, 2016 Our growing knowledge about various molecular mechanisms is becoming increasingly more structured and accessible. Different repositories of molecular interactions and available literature enable construction of focused and high-quality molecular ...
P. Gawron +10 more
semanticscholar +1 more source
Frontiers in Molecular Biosciences, 2020 Fluorescently labeled proteins can improve the detection sensitivity and have been widely used in a variety of biological measurements. In single-molecule assays, site-specific labeling of proteins enables the visualization of molecular interactions ...
Fang-Yuan Teng +13 more
doaj +1 more source
Enteric glia as a player of gut-brain interactions during Parkinson’s disease
Frontiers in Neuroscience, 2023 The enteric glia has been shown as a potential component of neuroimmune interactions that signal in the gut-brain axis during Parkinson’s disease (PD).
Beatriz Thomasi +6 more
doaj +1 more source
Mucoadhesion: mucin-polymer molecular interactions
International Journal of Pharmaceutics, 2021 Mucoadhesion, adhesion of a material to a mucous membrane or a mucus-covered surface, has been employed in drug delivery to prolong contact with adsorption sites and consequently a likely improvement of drug absorption. Mucoadhesion in the oral cavity also provides additional effects on tactile mouthfeel and extended flavor delivery, which impact ...
Quoc Dat, Pham +5 more
openaire +2 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Molecular Psychiatry, 2016 Numerous epidemiological studies have shown a significantly higher risk for development of Alzheimer’s disease (AD) in patients affected by type 2 diabetes (T2D), but the molecular mechanism responsible for this association is presently unknown.
I. Moreno-Gonzalez +5 more
semanticscholar +1 more source
Insights into T cell recognition of antigen: Significance of two-dimensional kinetic parameters
Frontiers in Immunology, 2012 The kinetic parameters governing T cell activation have been intensely studied for over a decade. However, the details of how the various aspects of receptor:ligand interactions culminate in T cell activation remains shrouded in mystery.
Lindsay J Edwards +4 more
doaj +1 more source