Results 21 to 30 of about 6,997,513 (404)

Marker and source-marker reprogramming of Most Permissive Boolean networks and ensembles with BoNesis [PDF]

open access: yesPeer Community Journal, 2023, 2022
Boolean networks (BNs) are discrete dynamical systems with applications to the modeling of cellular behaviors. In this paper, we demonstrate how the software BoNesis can be employed to exhaustively identify combinations of perturbations which enforce properties on their fixed points and attractors. We consider marker properties, which specify that some
arxiv   +1 more source

Current Molecular Markers of Melanoma and Treatment Targets

open access: yesInternational Journal of Molecular Sciences, 2020
Melanoma is a deadly skin cancer that becomes especially difficult to treat after it metastasizes. Timely identification of melanoma is critical for effective therapy, but histopathologic diagnosis can frequently pose a significant challenge to this goal.
Kevin Yang   +4 more
semanticscholar   +1 more source

Biomarker Exploration in Human Peripheral Blood Mononuclear Cells for Monitoring Sulforaphane Treatment Responses in Autism Spectrum Disorder [PDF]

open access: yes, 2020
Autism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders with no drugs treating the core symptoms and no validated biomarkers for clinical use.
Connors, Susan L.   +7 more
core   +3 more sources

Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders

open access: yesFrontiers in Aging Neuroscience, 2016
The overlap of symptoms between neurodegenerative and psychiatric diseases has been reported. Neuropsychiatric alterations are commonly observed in dementia, especially in the behavioral variant of frontotemporal dementia (bvFTD), which is the most ...
Roberta eZanardini   +3 more
doaj   +1 more source

The complete mitochondrial genome of Abramites hypselonotus (Günther, 1868) (Ostariophysi: Characiformes: Anostomidae): an aquarium headstander

open access: yesMitochondrial DNA. Part B. Resources, 2021
Abramites hypselonotus, commonly known as marbled headstander, is an important freshwater aquarium fish from Brazil, found in the Orinoco, Amazon, Paraguay and lower Parana River basins.
Adma Kátia Lacerda-Chaves   +2 more
doaj   +1 more source

Whole-genome sequencing for routine pathogen surveillance in public health : A population snapshot of invasive Staphylococcus aureus in Europe [PDF]

open access: yes, 2016
Funding Information: This work, including the efforts of Matthew Holden, Janina Dordel, Julian Parkhill, and Stephen Bentley, was funded by Wellcome Trust (098051). This work, including the efforts of David M. Aanensen, Corin Yeats, and Artemij Fedosejev,
ESCMID Study Group on Molecular Epidemiological Markers (ESGEM), European Staphylococcal Reference Laboratory Working Group
core   +1 more source

Molecular markers of sperm quality [PDF]

open access: yesReproduction in Domestic Ruminants, 2010
Light microscopic semen evaluation provides useful information about a given sperm sample, but due to its subjective nature has limited prognostic value for the reproductive performance of males or the outcome of assisted fertilization. Cryptic sperm abnormalities (occurring at the molecular level) are not easily detectable by light microscopy, but can
Peter Sutovsky, K W Lovercamp
openaire   +4 more sources

Genome Wide Association Study and Next Generation Sequencing: A Glimmer of Light Toward New Possible Horizons in Frontotemporal Dementia Research

open access: yesFrontiers in Neuroscience, 2019
Frontotemporal Dementia (FTD) is a focal neurodegenerative disease, with a strong genetic background, that causes early onset dementia. The present knowledge about the risk loci and causative mutations of FTD mainly derives from genetic linkage analysis,
Miriam Ciani   +4 more
doaj   +1 more source

Copper Imbalance in Alzheimer’s Disease: Meta-Analysis of Serum, Plasma, and Brain Specimens, and Replication Study Evaluating ATP7B Gene Variants

open access: yesBiomolecules, 2021
Evidence indicates that patients with Alzheimer’s dementia (AD) show signs of copper (Cu) dyshomeostasis. This study aimed at evaluating the potential of Cu dysregulation as an AD susceptibility factor.
Rosanna Squitti   +13 more
doaj   +1 more source

Analysis of a database of DNA profiles of 734 hybrid tea rose varieties [PDF]

open access: yes, 2009
Over 10,000 Hybrid Tea rose varieties have been described. The large number of varieties and the size of the reference collections may cause problems in DUS (Distinctiveness, Uniformity, and Stability) testing.
Esselink, G.   +3 more
core   +1 more source

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