Results 71 to 80 of about 2,144,828 (297)

Pan-urologic cancer genomic subtypes that transcend tissue of origin [PDF]

, 2017
Urologic cancers include cancers of the bladder, kidney, prostate, and testes, with common molecular features spanning different types. Here, we show that 1954 urologic cancers can be classified into nine major genomic subtypes, on the basis of ...
Bossé, Dominick, Chen, Fengju, Choueiri, Toni K, Creighton, Chad J, Gibbons, Don L, Hakimi, A. Ari, Hsieh, James J, Ittmann, Michael, Lalani, Aly-Khan A, Zhang, Yiqun   +9 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Tomato Molecular Markers

Journal of Fruit and Ornamental Plant Research, 2011
Tomato Molecular Markers Tomato ( Solanum lycopersicum L.) is one of the most popular vegetable grown in many regions of the world. Due to its high taste quality and nutritional value increase interest in the cultivation of this species and its consumption.
Wojciech Szczechura, Mirosława Staniaszek, Hanna Habdas   +2 more
openaire   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Loss of symbiotic and increase of virulent bacteria through microbial networks in Lynch syndrome colon carcinogenesis

Frontiers in Oncology
PurposeThrough a pilot study, we performed whole gut metagenomic analysis in 17 Lynch syndrome (LS) families, including colorectal cancer (CRC) patients and their healthy first-degree relatives.
Mohammad Sadeghi, Denis Mestivier, Etienne Carbonnelle, Robert Benamouzig, Khashayarsha Khazaie, Iradj Sobhani, Iradj Sobhani   +6 more
doaj   +1 more source

In-situ Formation of Amorphous Co-Al-P Layer on CoAl Layered Double Hydroxide Nanoarray as Neutral Electrocatalysts for Hydrogen Evolution Reaction

Frontiers in Chemistry, 2020
Exploration of high-efficiency and inexpensive electrode catalysts is of vital importance for the hydrogen evolution reaction (HER). In this research, an amorphous Co-Al-P layer was constructed on the surface of CoAl layered double hydroxide (CoAl-LDH ...
Wanqing Teng, Zhaomei Sun, Zhaomei Sun, Junfeng Xie, Ziqiang Wang, Xiangjiang Zheng, Bo Tang   +6 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Genetic relationships within and among Iberian fescues (Festuca L.) based on PCR-amplified markers

, 2006
The genus Festuca comprises approximately 450 species and is widely distributed around the world. The Iberian Penninsula, with more than 100 taxa colonizing very diverse habitats, is one of its main centers of diversification. This study was conducted to
Aiken S.G., Aiken S.G., Al-Bermani A.K.K.A., Bulinska-Radomska Z., Catalán P., Cebolla C., Cebolla C., Chusovljanov D.V., Consuelo Soler, Crowder L.V., Darbyshire S.J., de la Fuente V., de la Fuente V., de la Fuente V., de la Fuente V., de la Fuente V., de la Fuente V., Dellaporta S.L., Fletcher R., Holub J., Holub J., J.P. Gustafson, Jaccard P., Jenkin T.J., Juan V. Monte, Kerguélen M., Kerguélen M., Kulikov P.V., Kulikov P.V., Lehväslaiho H., Malik C.P., Marcelino de la Cruz, Page R.D.M., Pedro J.G. de Nova, Peto F.H., Saint-Yves A., Saint-Yves A., Sanderson M.J., Siffelova G., Stace C.A., Stammers M., Terrell E.E., Terrell E.E., Thompson J.D., Torrecilla P., Torrecilla P., Vos P., Williams J.G.K.   +47 more
core   +1 more source

Molecular markers: a potential resource for ginger genetic diversity studies [PDF]

, 2016
Ginger is an economically important and valuable plant around the world. Ginger is used as a food, spice, condiment, medicine and ornament. There is available information on biochemical aspects of ginger, but few studies have been reported on its ...
Ismail, Nor Asiah, Miah, Gous, Musa, Mohamed Hanafi, Tengku Muda Mohamed, Mahmud, Yusop, Mohd Rafii   +4 more
core   +1 more source