Results 81 to 90 of about 2,144,828 (297)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Modern approaches for breeding high quality apples with durable resistance to scab, powdery mildew and fire blight [PDF]

open access: yes, 2008
New methods to allow for more precise selection of tree and fruit characters in breeding programmes were developed in recent years. Marker-assisted selection (MAS) is common practice in the ACW apple breeding programme at Wädenswil.
Duffy, Brion   +3 more
core  

The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]

open access: yes, 2020
Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core  

Intersex related gene expression profiles in clams Scrobicularia plana : molecular markers and environmental application [PDF]

open access: yes, 2015
Intersex, the appearance of female characteristics in male gonads, has been identified in several aquatic species. It is a widespread phenomenon in populations of the bivalve, Scrobicularia plana, from the southwest coast of the U.K.
Alvarez-Munoz, Diana   +14 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Molecular markers for cacao traits [PDF]

open access: yes, 2012
Seventy-one microsatellites and 82 SNP markers were examined for their association with flush colour, shell content, seed butterfat content, fruit butterfat content, dry mass of cotyledons in a seed and dry mass of cotyledons from a fruit in 145 cacao ...
Boccara, Michel   +5 more
core  

Development and characterization of tri- and tetra-nucleotide polymorphic microsatellite markers for skipjack tuna (Katsuwonus pelamis) [PDF]

open access: yes, 2012
Skipjack tuna (katsuwonus pelamis) (SJT) is the largest tuna fishery in all the major oceans around the world, and the largest marine fishery in Sri Lanka. Knowledge of genetic population structure and effective population size of SJT in the Indian Ocean
Chand, Vincent   +2 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Selection for resistance to cacao Moniliasis assisted by molecular markers : S04P06 [PDF]

open access: yes, 2013
The basidiomycete Moniliophthora rorer, the etiological agent of Moniliasis, reaches cacao plantations (Theobroma cacao) in Central and South Americas, but its occurrence is still not registered in Brazil .
Clément, Didier   +3 more
core  

Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles [PDF]

open access: yes, 2012
Representative animal models for diabetes-associated vascular complications are extremely relevant in assessing potential therapeutic drugs. While several rodent models for type 2 diabetes (T2D) are available, their relevance in recapitulating renal and ...
Antonia Vlahou   +43 more
core   +3 more sources

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