Results 221 to 230 of about 1,749,054 (354)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Epigenetic modifications in ferroptosis regulation of breast cancer. [PDF]

Am J Cancer Res
Lin L, Wang Y, Si W, Liu X.
europepmc   +1 more source

Perspectives on mechanisms of gene regulation by 1,25-dihydroxyvitamin D3 and its receptor.

Journal of Steroid Biochemistry and Molecular Biology, 2007
J. Pike, M. Meyer, Makoto Watanuki, Sungtae Kim, Lee A. Zella, Jackie A. Fretz, M. Yamazaki, N. Shevde   +7 more
semanticscholar   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

MPK3 as a Signalling Hub in Plants: Integrating Plant Growth, Development and Stress Response. [PDF]

Plants (Basel)
Gao F, Qi X, Guo H, Wang W, Liu F, Zeng X, Song B, Cheng L, Fan Y, Zeng F.   +9 more
europepmc   +1 more source

Regulation of heat-shock genes in bacteria: from signal sensing to gene expression output

FEMS Microbiology Reviews, 2017
Davide Roncarati, V. Scarlato
semanticscholar   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

From calcium pump to metabolic hub: emerging genetic phenotypes and metabolic networks of SERCA2 in skeletal muscle. [PDF]

Front Physiol
Lei S, Qu Y, Yan J, Nan F, Liu S, Pan W, Yu C.   +6 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Microarray Data Analysis of Gene Crosstalk Between Psoriasis and Non-Alcoholic Fatty Liver Disease. [PDF]

Clin Cosmet Investig Dermatol
Tan Y, Xu C, Xiao Y, Song W, Zhang Y, Yang Z, Chen A, Wu Q.   +7 more
europepmc   +1 more source