FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Molecular pathways in vascular cognitive impairment and dementia: focus on synaptic plasticity and epigenetic modifications. [PDF]
Front Aging NeurosciLiu C +7 more
europepmc +1 more source
Molecular mechanisms regulating the transcription of an organizer-specific gene: chordin
Developmental Biology, 2008 Zhang, Yan, Sheets, Michael
openaire +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Glycolytic lactylation modulates cell death decisions in diabetic kidney disease: Metabolic‑epigenetic interplay between ferroptosis and autophagy in fibrotic remodeling (Review). [PDF]
Int J Mol MedZhang T +7 more
europepmc +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Molecular and Cellular Mechanisms of Plant Responses to Heavy Metal Stress in Mining-Impacted Environments. [PDF]
Plants (Basel)Ioniță MF, Dunca EC, Radu SM.
europepmc +1 more source
Molecular mechanisms involved in TNF - and gastrin-mediated gene regulation
, 2001 Cells in a multicellular organism depend on extensive communication with each other. Eukaryotic cells have developed elaborate signal transduction systems by which externally provided information (hormones, cytokines, growth factors, ions and other signaling molecules) is converted into intracellular information that regulates the internal workings of ...
openaire +1 more source
Molecular mechanism of endothelial growth arrest by laminar shear stress.
Proceedings of the National Academy of Sciences of the United States of America, 2000 Kurt M. Lin +8 more
semanticscholar +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source