Results 91 to 100 of about 4,358,128 (358)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Small but mighty: mitochondrial DNA at the centre of retrograde signalling

Cell Communication and Signaling
Mitochondria form highly dynamic and interconnected networks that continuously communicate with the cytoplasm and the nucleus to maintain cellular homeostasis and coordinate adaptive responses to stress.
Eve Harding, Veronica Bazzani, Carlo Vascotto   +2 more
doaj   +1 more source

Macroscopic transport by synthetic molecular machines [PDF]

, 2005
Nature uses molecular motors and machines in virtually every significant biological process, but demonstrating that simpler artificial structures operating through the same gross mechanisms can be interfaced with—and perform physical tasks in—the ...
A Altieri, AH Flood, AN Tamovsky, AW Neumann, B Long, BS Gallardo, D-H Qu, DA Leigh, David A. Leigh, DC Blomstrom, E Katz, E Katz, EM Pérez, Emilio M. Pérez, ER Kay, F Brochard, F Cecchet, Francesco Zerbetto, G Bottari, Gilberto Teobaldi, H Gau, H Hess, H Hess, H Liu, H Noji, H-R Tseng, HP Greenspan, José Berná, K Ichimura, K Kim, M Cavallini, M Grunze, MK Chaudhury, Monika Lubomska, NJ Pienta, Petra Rudolf, PJ Kropp, Q-C Wang, RK Soong, RK Soong, S Daniel, S Diez, S-K Oh, Sandra M. Mendoza, SS Jang, TJ Huang, TJ Huang, V Balzani, V Balzani, Y Liu, Y Masaaki   +50 more
core   +4 more sources

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Studies of molecular mechanisms integrating carbon metabolism and growth in plants [PDF]

, 2003
Plants use light energy, carbon dioxide and water to produce sugars and other carbohydrates, which serve as stored energy reserves and as building blocks for biosynthetic reactions.
Thelander, Mattias
core  

A Molecular Implementation of the Least Mean Squares Estimator

, 2017
In order to function reliably, synthetic molecular circuits require mechanisms that allow them to adapt to environmental disturbances. Least mean squares (LMS) schemes, such as commonly encountered in signal processing and control, provide a powerful ...
Khammash, Mustafa, Zechner, Christoph
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Molecular mechanisms that stabilize short term synaptic plasticity during presynaptic homeostatic plasticity. [PDF]

, 2018
Presynaptic homeostatic plasticity (PHP) compensates for impaired postsynaptic neurotransmitter receptor function through a rapid, persistent adjustment of neurotransmitter release, an effect that can exceed 200%.
Davis, Graeme W, Genç, Özgür, Ortega, Jennifer M   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source