Results 71 to 80 of about 6,482,931 (261)

Molecular mechanisms of autoimmunity

open access: yesAutoimmunity, 2008
Autoimmunity is mediated by a variety of mechanisms, molecular and cellular events, and responses. Predisposition to a given autoimmune response requires the requisite allele(s) that controls antigen presentation by antigen-presenting cells for T cell recognition.
M. Zouhair Atassi   +3 more
openaire   +2 more sources

The epigenetic circle: feedback loops in the maintenance of cellular memory

open access: yesEpigenetics & Chromatin
The memory of gene expression states, active or repressive, is a fundamental biological concept as it controls cell fate in development, immunity and abiotic stress responses.
Marko Tomljanović   +3 more
doaj   +1 more source

Uncovering the Invisible: Mono-ADP-ribosylation Moved into the Spotlight

open access: yesCells, 2021
Adenosine diphosphate (ADP)-ribosylation is a nicotinamide adenine dinucleotide (NAD+)-dependent post-translational modification that is found on proteins as well as on nucleic acids.
Ann-Katrin Hopp, Michael O. Hottiger
doaj   +1 more source

Molecular Mechanisms for Coping with Al Toxicity in Plants

open access: yes, 2019
Aluminum (Al) toxicity is one of the major constraints to agricultural production in acid soils. Molecular mechanisms of coping with Al toxicity have now been investigated in a range of plant species.
Jingjing Huang   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Regulation of Glucose Metabolism by NAD+ and ADP-Ribosylation

open access: yesCells, 2019
Cells constantly adapt their metabolic pathways to meet their energy needs and respond to nutrient availability. During the last two decades, it has become increasingly clear that NAD+, a coenzyme in redox reactions, also mediates several ubiquitous cell
Ann-Katrin Hopp   +2 more
doaj   +1 more source

Combination of Nicorandil and Beta-Adrenergic Receptor Blockers in Patients with Coronary Artery Disease: A Real-World Observational Study

open access: yesJournal of Cardiovascular Pharmacology and Therapeutics, 2023
Background The effect of combined nicorandil and beta-adrenergic receptor blockers (BBs) compared with that of BBs alone on long-term clinical outcomes in patients with coronary artery disease (CAD) remains undetermined.
Jia Cheng MD, PhD   +6 more
doaj   +1 more source

Molecular Mechanisms of Reconsolidation-Dependent Memory Updating

open access: yes, 2020
Memory is not a stable record of experience, but instead is an ongoing process that allows existing memories to be modified with new information through a reconsolidation-dependent updating process.
Lauren Bellfy, Janine L. Kwapis
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

TUBB4B Downregulation Is Critical for Increasing Migration of Metastatic Colon Cancer Cells

open access: yesCells, 2019
Tumor metastasis, the major problem for clinical oncology in colon cancer treatment, is linked with an epithelial-mesenchymal transition (EMT). The observed cellular transformation in this process is manifested by cell elongation, enhanced cell migration
Katarzyna Sobierajska   +7 more
doaj   +1 more source

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