Results 11 to 20 of about 14,308,960 (385)
Molecular mechanisms of etoposide [PDF]
EXCLI journal, 2015 EXCLI Journal ; Vol.
Montecucco A, Zanetta F, Biamonti G
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Molecular Mechanisms of Hepatoblastoma [PDF]
Seminars in Liver Disease, 2021 AbstractHepatoblastoma (HB) is the predominant primary liver tumor in children. While the prognosis is favorable when the tumor can be resected, the outcome is dismal for patients with progressed HB. Therefore, a better understanding of the molecular mechanisms responsible for HB is imperative for early detection and effective treatment.
Stefano Cairo +6 more
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Current Pharmaceutical Design, 2014 Molecular Mechanics (MM) force fields are the methods of choice for protein simulations, which are essential in the study of conformational flexibility. Given the importance of protein flexibility in drug binding, MM is involved in most if not all Computational Structure-Based Drug Discovery (CSBDD) projects.
Vanommeslaeghe, Kenno +2 more
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Molecular Mechanisms of Preeclampsia [PDF]
Journal of Pregnancy, 2012 Preeclampsia is one of the leading causes of maternal morbidity/mortality. The pathogenesis of preeclampsia is still under investigation. The aim of this paper is to present the molecular mechanisms implicating in the pathway leading to preeclampsia.
Nikolaos Vitoratos +2 more
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On the molecular mechanisms of transposition. [PDF]
Proceedings of the National Academy of Sciences, 1981 We present a model for transposition that allows a choice between cointegrate formation (replicon fusion) and direct transposition. We propose that initiation of the process occurs by invasion of the target DNA by a single-stranded end of the transposable element.
Galas, David J., Chandler, Michael
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HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides
Nature Communications, 2022 HAESA and HSL2 are receptors for IDA/IDL-family signaling peptides in plants. Here the authors show that HSL1, previously shown to recognize CLE9, preferentially binds IDA/IDL peptides and regulates leaf epidermal patterning independently of CLE peptides.
Andra-Octavia Roman +5 more
doaj +1 more source
Ferroptosis: molecular mechanisms and health implications
Cell Research, 2020 Cell death can be executed through different subroutines. Since the description of ferroptosis as an iron-dependent form of non-apoptotic cell death in 2012, there has been mounting interest in the process and function of ferroptosis.
D. Tang, Xin Chen, R. Kang, G. Kroemer
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Cell Death and Disease, 2022 Triple-negative breast cancer (TNBC) is clinically defined by the absence of estrogen and progesterone receptors and the lack of membrane overexpression or gene amplification of receptor tyrosine kinase ErbB-2/HER2.
Santiago Madera +18 more
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Molecular Mechanisms of Endocytosis [PDF]
Cell, 1997 Cells regulate their developmental and functional programs through their interaction with the external milieu, which requires communication across the plasma membrane. The plasma membrane is constantly being remodeled by endocytosis allowing cells to control how they respond to external stimuli.
Riezman, H. +3 more
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Cancer Cell International, 2023 Background Cancer-secreted exovesicles are important for cell-to-cell communication by altering cancer-related signalling pathways. Exovesicles-derived miRNAs (exomiRNAs)-target genes can be useful for diagnostic and prognostic purposes. Methods ExomiRNA
Antonio Altuna-Coy +4 more
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