Results 211 to 220 of about 6,482,931 (261)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Mechanisms of Drug Resistance in Glioblastoma
International Journal of Molecular Sciences, 2021 Glioblastoma multiforme (GBM) is the most common and fatal primary brain tumor, is highly resistant to conventional radiation and chemotherapy, and is not amenable to effective surgical resection.
Maya Dymova +2 more
exaly +2 more sources
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Molecular mechanisms of cellular mechanics
Physical Chemistry Chemical Physics, 2006Mechanical forces play an essential role in cellular processes as input, output, and signals. Various protein complexes in the cell are designed to handle, transform and use such forces. For instance, proteins of muscle and the extracellular matrix can withstand considerable stretching forces, hearing-related and mechanosensory proteins can transform ...
Mu, Gao +4 more
openaire +2 more sources
Molecular mechanisms of photocarcinogenesis
Frontiers in Bioscience, 2002Photocarcinogenesis represents the accumulation of genetic changes as well as immune system modulation, which ultimately lead to the development of skin cancers. The recent advances in molecular and cellular biology have clarified the mechanisms of photocarcinogenesis, including the formation of DNA photoproducts, DNA repair, mutation of proto ...
Yasuhiro, Matsumura +1 more
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Molecular mechanisms in cardiomyopathy
Clinical Science, 2017Cardiomyopathies represent a heterogeneous group of diseases that negatively affect heart function. Primary cardiomyopathies specifically target the myocardium, and may arise from genetic [hypertrophic cardiomyopathy (HCM), arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D), mitochondrial cardiomyopathy] or genetic and acquired [dilated
Keith, Dadson +2 more
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Molecular mechanisms of forgetting
European Journal of Neuroscience, 2020Abstract The field of learning and memory has largely focused their efforts on memory formation, deeming the act of forgetting as a necessary and unavoidable error of the brain's storage system. However, recent studies show that forgetting might be a purposeful mechanism with dedicated molecular pathways.
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Molecular Mechanism of Contraction
Annual Review of Biophysics and Bioengineering, 1972This review is an attempt to summarize critically significant, recent contribu tions to our understanding of the molecular mechanism of muscle contraction and cell motility; it does not cover all the work on muscle contraction. Nat urally, the authors have tended to emphasize their own interests and their own approaches to the problem.
Y, Tonomura, F, Oosawa
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Molecular mechanisms of photosensitization
Biochimie, 1986The first part of this article is devoted to basic concepts of photosensitization and to the primary photophysical and photochemistry processes involved in the reaction. The electronic configuration of molecular oxygen in its ground or activated states, which intervene in numerous photosensitized reactions, is reviewed.
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Molecular Mechanisms of Oncogenesis
1990Cellular oncogenes (c-oncs) have been highly conserved throughout evolution and subserve important roles in growth and development. Both in development and the neoplastic state, c-oncs appear to collaborate rather than function independently. Cellular oncogenes are activated in the neoplastic process by four (nonviral) mechanisms; (a) chromosomal ...
T A, Seemayer, W K, Cavenee
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