Results 231 to 240 of about 4,358,128 (358)

Molecular Mechanisms of Venom Diversity. [PDF]

Toxins (Basel)
Ishihara MA, Lopes AR, Nishiyama-Jr MY.
europepmc   +1 more source

Molecular mechanism of sarcopenia

Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2018
openaire   +3 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Advancements and innovations in the molecular mechanisms and treatment of colorectal cancer. [PDF]

Discov Oncol
Wang X, Yang J.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Editorial: Enhancing adrenal tumor diagnostics: biomarkers and molecular mechanisms. [PDF]

Front Endocrinol (Lausanne)
Glinicki P, Falhammar H.
europepmc   +1 more source

Molecular Mechanism of Golden Pomfret Myofibrillar Protein Digestion Inhibition by Malondialdehyde-Mediated Oxidation Based on Peptidomics Analysis

Zefu Wang, Guanyi Chen, Xiaosi Chen, Qiuyu Xia, Yantao Yin, Naiyong Xiao, Shucheng Liu   +6 more
openalex   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Special Issue: "Molecular Mechanisms and Regulation in Chronic Kidney Diseases". [PDF]

Int J Mol Sci
Delrue C, Delanghe JR, Speeckaert MM.
europepmc   +1 more source

Molecular mechanisms regulating lymphangiogenesis

, 2017
Sanja Coso
openalex   +1 more source