Results 51 to 60 of about 14,308,960 (385)

Molecular Mechanisms in Melanoma [PDF]

New England Journal of Medicine, 2006
The review of melanoma by Mil- ler and Mihm (July 6 issue)1 clearly characterizes the linear progression of melanocytic lesions, from the morphologic perspective to the molecular per- spective.2,3 However, the genetic alterations would have more relevance if they result in kinetic ad- vantage and progression.
openaire   +2 more sources

Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism

Journal of Experimental & Clinical Cancer Research, 2019
Background Thyroid carcinoma includes several variants characterized by different biological and clinical features: from indolent microcarcinoma to undifferentiated and aggressive anaplastic carcinoma. Inflammation plays a critical role in thyroid tumors.
Mara Mazzoni, Giuseppe Mauro, Marco Erreni, Paola Romeo, Emanuela Minna, Maria Grazia Vizioli, Cristina Belgiovine, Maria Grazia Rizzetti, Sonia Pagliardini, Roberta Avigni, Maria Chiara Anania, Paola Allavena, Maria Grazia Borrello, Angela Greco   +13 more
doaj   +1 more source

Transcriptomic landscape of TIMP3 oncosuppressor activity in thyroid carcinoma

Cancer Cell International, 2022
Background Papillary thyroid cancer (PTC) is the most frequent thyroid tumor. The tissue inhibitor of metalloproteinase-3 (TIMP3) gene encodes a matrix metalloproteinases inhibitor that exerts a tumor suppressor role in several tumor types.
M. Mazzoni, K. Todoerti, L. Agnelli, E. Minna, S. Pagliardini, T. Di Marco, M. G. Borrello, A. Neri, A. Greco   +8 more
doaj   +1 more source

Molecular mechanisms of luteinization [PDF]

Obstetrics & Gynecology Science, 2014
Dynamic changes in steroidogenesis occur in ovarian granulosa cells during ovulation after the LH surge. The ovulatory LH surge induces rapid up-regulation of steroidogenic acute regulatory (StAR) protein and rapid down-regulation of aromatase (Cyp19a1) in granulosa cells undergoing luteinization during ovulation.
openaire   +3 more sources

Molecular Mechanisms Used by Salmonella to Evade the Immune System [PDF]

, 2017
Human and animal pathogens are able to circumvent, at least temporarily, the sophisticated immune defenses of their hosts. Several serovars of the Gram-negative bacterium Salmonella enterica have been used as models for the study of pathogen-host ...
Bernal Bayard, Joaquín, Ramos Morales, Francisco   +1 more
core   +1 more source

Role of a Heat Shock Transcription Factor and the Major Heat Shock Protein Hsp70 in Memory Formation and Neuroprotection

Cells, 2021
Heat shock proteins (Hsps) represent the most evolutionarily ancient, conserved, and universal system for protecting cells and the whole body from various types of stress.
Olga G. Zatsepina, Michael B. Evgen’ev, David G. Garbuz   +2 more
doaj   +1 more source

Molecular Mechanisms of Glucocorticoid-Induced Insulin Resistance

International Journal of Molecular Sciences, 2021
Glucocorticoids (GCs) are steroids secreted by the adrenal cortex under the hypothalamic-pituitary-adrenal axis control, one of the major neuro-endocrine systems of the organism.
C. Beaupere, Alexandrine Liboz, B. Fève, B. Blondeau, G. Guillemain   +4 more
semanticscholar   +1 more source

Plant responses to photoperiod [PDF]

, 2009
Photoperiod controls many developmental responses in animals, plants and even fungi. The response to photoperiod has evolved because daylength is a reliable indicator of the time of year, enabling developmental events to be scheduled to coincide with ...
Abe, Achard, Adams, Adams, Alabadi, An, Asai, Aukerman, Balasubramanian, Banerjee, Batutis, Beales, Ben-Naim, Berardini, Bernier, Blazquez, Blázquez, Blázquez, Bollman, Bongard-Pierce, Borchert, Bouveret, Bäurle, Böhlenius, Cerdán, Chae, Chailkhyan, Chen, Chen, Chien, Chincinska, Clarke, Cockcroft, Corbesier, David, Devlin, Doi, Dudley, Duncan, Fahlgren, Farré, Foster, Fowler, Gandikota, Gardner, Giavalisco, Goldman, Gonthier, Grigg, Hackett, Halliday, Hayama, Hayama, Haywood, He, He, Henderson, Heyer, Holm, Hotta, Hsu, Hunter, Hunter, Imaizumi, Imaizumi, Izawa, Jackson, Jackson, Jackson, Jackson, Jaeger, Jang, Jung, Kanrar, Kelly, Kim, Kim, Kim, Kim, Kojima, Komiya, Kotake, Kusnetsov, Laubinger, Lauter, Lee, Lee, Lin, Martinez-Garcia, Martínez, Mathieu, McClung, Michael, Moon, Mouradov, Más, Nilsson, Onouchi, Orkwiszewski, Osterlund, Park, Peragine, Pineiro, Poethig, Poethig, Pouteau, Razem, Reeves, Roberts, Robinson, Robson, Roden, Rodriguez-Falcon, Saijo, Samach, Sawa, Schmid, Schwarz, Searle, Seo, Singer, Sivitz, Smith, Somers, Souer, Stadler, Steward, Suàrez-López, Swiezewski, Takada, Takeno, Tamaki, Telfer, Tessadori, Thomas, Turner, Valverde, Vega, Von Arnim, Wang, Wang, Weigel, Wenkel, Wigge, Willmann, Wu, Xie, Yamaguchi, Yan, Yanovsky, Yanovsky, Yoo, Yoo, Yu, Zeevaart   +154 more
core   +1 more source

Hypoxia- and MicroRNA-Induced Metabolic Reprogramming of Tumor-Initiating Cells

Cells, 2019
Colorectal cancer (CRC), the second most common cause of cancer mortality in the Western world, is a highly heterogeneous disease that is driven by a rare subpopulation of tumorigenic cells, known as cancer stem cells (CSCs) or tumor-initiating cells ...
Pit Ullmann, Martin Nurmik, Rubens Begaj, Serge Haan, Elisabeth Letellier   +4 more
doaj   +1 more source

Abstract P-5: Modern Membrane Mimetic Systems for Cryo-EM Based Structural Analysis [PDF]

International Journal of Biomedicine, 2019
Background: Single particle approach that is used to image the sample by an electron beam requires receptors to be extracted from the cell membrane and placed into the sample grid in the solubilized form.
Egor S. Kolesnikov, Polina A. Khorn, Anastasiia U. Gusach, Aleksandra P. Luginina, Alexey V. Mishin   +4 more
doaj   +1 more source