Results 71 to 80 of about 4,304,368 (356)

Desorption From Interstellar Ices

open access: yes, 2007
The desorption of molecular species from ice mantles back into the gas phase in molecular clouds results from a variety of very poorly understood processes.
Creighan   +4 more
core   +1 more source

Macroscopic transport by synthetic molecular machines [PDF]

open access: yes, 2005
Nature uses molecular motors and machines in virtually every significant biological process, but demonstrating that simpler artificial structures operating through the same gross mechanisms can be interfaced with—and perform physical tasks in—the ...
A Altieri   +50 more
core   +4 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Tumoral periprostatic adipose tissue exovesicles-derived miR-20a-5p regulates prostate cancer cell proliferation and inflammation through the RORA gene

open access: yesJournal of Translational Medicine
Background From the first steps of prostate cancer (PCa) initiation, tumours are in contact with the most-proximal adipose tissue called periprostatic adipose tissue (PPAT).
Silvia Sánchez-Martin   +8 more
doaj   +1 more source

Molecular mechanisms of autoimmunity triggered by microbial infection [PDF]

open access: yes, 2005
Autoimmunity can be triggered by microbial infection. In this context, the discovery of Toll-like receptors (TLRs) provides new insights and research perspectives.
Anders, Hans-Joachim   +3 more
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Molecular Motors Interacting with Their Own Tracks

open access: yes, 2007
Dynamics of molecular motors that move along linear lattices and interact with them via reversible destruction of specific lattice bonds is investigated theoretically by analyzing exactly solvable discrete-state ``burnt-bridge'' models.
A. Y. Morozov   +4 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Investigating the Molecular Mechanisms of Pepper Fruit Tolerance to Storage via Transcriptomics and Metabolomics [PDF]

open access: gold, 2021
Hao Sun   +11 more
openalex   +1 more source

Molecular Mechanisms of Schizophrenia [PDF]

open access: yesCellular Physiology and Biochemistry, 2007
Schizophrenia is a complex disorder, where family, twin and adoption studies have been demonstrating a high heritability of the disease and that this disease is not simply defined by several major genes but rather evolves from addition or potentiation of a specific cluster of genes, which subsequently determines the genetic vulnerability of an ...
Undine E, Lang   +4 more
openaire   +2 more sources

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