Results 81 to 90 of about 36,527 (232)
AA amyloidosis: basic knowledge, unmet needs and future treatments
Systemic AA amyloidosis is a long-term complication of several chronic inflammatory disorders, including rheumatoid arthritis, ankylosing spondylitis, autoinflammatory syndromes, Crohn’s disease, malignancies and conditions predisposing to ...
Laura Obici, Giampaolo Merlini
doaj +1 more source
Molecular Docking of Monomethine Cyanine Dyes to Lysozyme Amyloid Fibrils
Protein aggregation into highly ordered supramolecular aggregates is the hallmark of many degenerative diseases including the neurological disorders (Parkinson’s, Alzheimer’s, and Huntington’s diseases), type II diabetes, systemic amyloidosis, spongiform
Olga Zhytniakivska +5 more
doaj +1 more source
Localized Nasopharyngeal Amyloidosis [PDF]
A mass in the nasopharynx often implies a malignancy in adults, particularly in the endemic areas of Epstein-Barr virus-associated undifferentiated carcinoma.
Abrams, K. +7 more
core +2 more sources
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer +25 more
wiley +1 more source
Consumed by Abdominal Distention
Arthritis Care &Research, Accepted Article.
Abimbola Fadairo‐Azinge +3 more
wiley +1 more source
Hereditary transthyretin amyloidosis (hATTR) with polyneuropathy (formerly known as Familial Amyloid Polyneuropathy (FAP)) is an endemic amyloidosis involving the harmful aggregation of proteins, most commonly transthyretin (TTR) but sometimes also ...
Per M. Roos +1 more
doaj +1 more source
Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology
The hormone islet amyloid polypeptide (IAPP, or amylin) plays a role in glucose homeostasis but aggregates to form islet amyloid in type-2 diabetes. Islet amyloid formation contributes to β-cell dysfunction and death in the disease and to the failure of ...
Rehana Akter +10 more
doaj +1 more source
Background The complex pathophysiology of Alzheimer’s disease (AD) hampers the development of effective treatments. Attempts to prevent neurodegeneration in AD have failed so far, highlighting the need for further clarification of the underlying cellular
Gonzalo Ruiz-Pérez +13 more
doaj +1 more source
Serum amyloid A (SAA) : Proinflammatory functions and their regulation by serum lipoproteins [PDF]
The immune response is operated by two integrated systems, the adaptive and innate immune responses. Innate immunity includes both cellular and soluble components.
Niemi, Katri
core
Anti-Inflammatory activity of a polyphenolic extract from Arabidopsis thaliana in in vitro and in vivo models of Alzheimer's Disease [PDF]
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. One of the main features of AD is the increase in amyloid-beta (Aβ) peptide production and aggregation, leading to oxidative stress ...
Casale, Assunta Maria +10 more
core +1 more source

