Results 81 to 90 of about 36,527 (232)

AA amyloidosis: basic knowledge, unmet needs and future treatments

open access: yesSwiss Medical Weekly, 2012
Systemic AA amyloidosis is a long-term complication of several chronic inflammatory disorders, including rheumatoid arthritis, ankylosing spondylitis, autoinflammatory syndromes, Crohn’s disease, malignancies and conditions predisposing to ...
Laura Obici, Giampaolo Merlini
doaj   +1 more source

Molecular Docking of Monomethine Cyanine Dyes to Lysozyme Amyloid Fibrils

open access: yesEast European Journal of Physics, 2022
Protein aggregation into highly ordered supramolecular aggregates is the hallmark of many degenerative diseases including the neurological disorders (Parkinson’s, Alzheimer’s, and Huntington’s diseases), type II diabetes, systemic amyloidosis, spongiform
Olga Zhytniakivska   +5 more
doaj   +1 more source

Localized Nasopharyngeal Amyloidosis [PDF]

open access: yes, 2010
A mass in the nasopharynx often implies a malignancy in adults, particularly in the endemic areas of Epstein-Barr virus-associated undifferentiated carcinoma.
Abrams, K.   +7 more
core   +2 more sources

Exercise limitations in amyloid cardiomyopathy assessed by cardiopulmonary exercise testing—A multicentre study

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer   +25 more
wiley   +1 more source

Consumed by Abdominal Distention

open access: yes
Arthritis Care &Research, Accepted Article.
Abimbola Fadairo‐Azinge   +3 more
wiley   +1 more source

Hereditary Transthyretin Amyloidosis (hATTR) with Polyneuropathy Clusters Are Located in Ancient Mining Districts: A Possible Geochemical Origin of the Disease

open access: yesBiomolecules
Hereditary transthyretin amyloidosis (hATTR) with polyneuropathy (formerly known as Familial Amyloid Polyneuropathy (FAP)) is an endemic amyloidosis involving the harmful aggregation of proteins, most commonly transthyretin (TTR) but sometimes also ...
Per M. Roos   +1 more
doaj   +1 more source

Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

open access: yesJournal of Diabetes Research, 2016
The hormone islet amyloid polypeptide (IAPP, or amylin) plays a role in glucose homeostasis but aggregates to form islet amyloid in type-2 diabetes. Islet amyloid formation contributes to β-cell dysfunction and death in the disease and to the failure of ...
Rehana Akter   +10 more
doaj   +1 more source

Potentiation of amyloid beta phagocytosis and amelioration of synaptic dysfunction upon FAAH deletion in a mouse model of Alzheimer's disease

open access: yesJournal of Neuroinflammation, 2021
Background The complex pathophysiology of Alzheimer’s disease (AD) hampers the development of effective treatments. Attempts to prevent neurodegeneration in AD have failed so far, highlighting the need for further clarification of the underlying cellular
Gonzalo Ruiz-Pérez   +13 more
doaj   +1 more source

Serum amyloid A (SAA) : Proinflammatory functions and their regulation by serum lipoproteins [PDF]

open access: yes, 2012
The immune response is operated by two integrated systems, the adaptive and innate immune responses. Innate immunity includes both cellular and soluble components.
Niemi, Katri
core  

Anti-Inflammatory activity of a polyphenolic extract from Arabidopsis thaliana in in vitro and in vivo models of Alzheimer's Disease [PDF]

open access: yes, 2019
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. One of the main features of AD is the increase in amyloid-beta (Aβ) peptide production and aggregation, leading to oxidative stress ...
Casale, Assunta Maria   +10 more
core   +1 more source

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