Results 91 to 100 of about 4,511,721 (218)
Microbial risk factors of cardiovascular and cerebrovascular diseases: potential therapeutic options [PDF]
, 2008 Infection and inflammation may have a crucial role in the pathogenesis of atherosclerosis. This hypothesis is supported by an increasing number of reports on the interaction between chronic infection, inflammation, and atherogenesis.
Abbas, M.A. +6 more
core +1 more source
The Gut Microbiome in Neuromyelitis Optica. [PDF]
, 2017 Neuromyelitis optica (NMO) is a rare, disabling, sometimes fatal central nervous system inflammatory demyelinating disease that is associated with antibodies ("NMO IgG") that target the water channel protein aquaporin-4 (AQP4) expressed on astrocytes ...
Baranzini, Sergio E +3 more
core +1 more source
Seronegative spondyloarthropathies : a review : part II: genetics and pathogenesis [PDF]
, 1993 In none of the spondyloarthropathies is the pathogenesis well understood. Much of the investigation into the aetio-pathogenesis of these diseases has focused on the association with HLA-B27 and the known triggering potential of certain infectious agents.
Borg, Andrew A. +2 more
core
, 2018 We take the potentialities that are studied in the biological sciences (e.g., totipotency) to be an important subtype of biological dispositions. The goal of this paper is twofold: first, we want to provide a detailed understanding of what biological ...
A Bird +37 more
core +1 more source
Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance This work shows that the amidated terminal ends of the secreted hypocretin (HCRT) peptides (HCRTNH2) are autoantigens in type 1 narcolepsy, an autoimmune disorder targeting HCRT neurons.
Guo Luo +7 more
semanticscholar +1 more source
Drosophila as a model system to study nonautonomous mechanisms affecting tumour growth and cell death [PDF]
, 2018 The study of cancer has represented a central focus in medical research for over a century. The great complexity and constant evolution of the pathology require the use of multiple research model systems and interdisciplinary approaches.
Cordero, Julia B. +2 more
core +3 more sources
Molecular mimicry: Basis for autoimmunity [PDF]
Indian Journal of Clinical Biochemistry, 2000 Structural similarity between a viral protein and a self-component can trigger an autoimmune response, which is the basis of molecular mimicry. Alternatively an invading virus can induce an inflammatory response which in turn can initiate an attack by hitherto dormant T cells on a specific self-antigen, a phenomenon which is referred to as Bystander ...
openaire +2 more sources
altered expression of cD300a inhibitory receptor on cD4+ T cells From human immunodeficiency Virus-1-infected Patients: association With Disease Progression Markers. [PDF]
, 2018 The ability of the CD300a inhibitory receptor to modulate immune cell functions and its involvement in the pathogenesis of many diseases has aroused a great interest in this molecule.
Genebat González, Miguel +3 more
core +1 more source
Cancer Biology & MedicineMelanoma, the most aggressive form of skin cancer, remains a significant clinical challenge due to the high metastatic potential and drug resistance. This review explores the pivotal roles of angiogenesis and vasculogenic mimicry in melanoma progression ...
Simona Serratì +9 more
doaj +1 more source
Microbiota and chronic inflammatory arthritis. an interwoven link [PDF]
, 2016 Background: Only recently, the scientific community gained insights on the importance of the intestinal resident flora for the host's health and disease.
D'Amelio, Raffaele +3 more
core +2 more sources