Results 101 to 110 of about 2,281 (156)
Mimicry Not Replacement: Molecular Engineering Transforms the Outlook in Hemophilia A
, 2018 Paul Moss
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Diverse genetic conflicts mediated by molecular mimicry and computational approaches to detect them
Shelbi L. Russell +2 more
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Parasitology Today, 1987
The host immune response is an important line of defence against parasites. Tactics to evade this response are therefore expected in host-parasite relationships, and the clearest example is the antigenic variation displayed by African trypanosomes. But while few other parasites seem to have quite this ability, many seem to display a form of antigenic ...
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The host immune response is an important line of defence against parasites. Tactics to evade this response are therefore expected in host-parasite relationships, and the clearest example is the antigenic variation displayed by African trypanosomes. But while few other parasites seem to have quite this ability, many seem to display a form of antigenic ...
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Molecular mimicry or structural mimicry?
Molecular Immunology, 2006"Molecular mimicry" should be changed to "structural mimicry". The immune system recognizes shapes--three-dimensional shapes--not sequences. For two sequences to act biologically similar they must possess similar three-dimensional structures.
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Molecular Mimicry and Autoimmunity
New England Journal of Medicine, 1999Autoimmune disease is the consequence of an immune response against self-antigens that results in the damage and eventual dysfunction of target organs. Although the triggering event in most autoimmune diseases is unknown, an infectious cause has long been postulated to explain the development of autoimmunity. Molecular mimicry is one mechanism by which
L J, Albert, R D, Inman
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Molecular Mimicry in Multiple Sclerosis
New England Journal of Medicine, 2003Molecular mimicry is a model in which foreign antigens are sufficiently similar to native antigens to trigger an autoimmune response. A study involving the specificity of a T-cell receptor derived from a patient with multiple sclerosis indicates that molecular mimicry extends to complexes of proteins — a finding with implications for therapy.
Wekerle, H., Hohlfeld, R.
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Chemokine receptors and molecular mimicry
Immunology Today, 1994Chemokines are small pro-inflammatory peptides that are best known for their leukocyte-chemoattractant activity. The cloned leukocyte chemokine receptors, interleukin 8 receptor (IL-8R) types A and B and the macrophage inflammatory protein 1 alpha (MIP-1 alpha)/RANTES receptor, are related by sequence and chemokine binding to two herpesvirus products ...
S K, Ahuja, J L, Gao, P M, Murphy
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Molecular mimicry and auto-immunity
Clinical Reviews in Allergy & Immunology, 2007The term "molecular mimicry" was coined by R. Damian in 1964, who was first to suggest that antigenic determinants of micro-organisms may resemble antigenic determinants of their host. Damian suggested that this similarity served as a defense mechanism of a microorganism from the host's immune system and prevented the development of immune response to ...
Miri, Blank +2 more
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