Results 241 to 250 of about 3,812,700 (365)

Developmental Hypoxia Enhances Kidney Organoid Complexity and Maturity

Advanced Science, EarlyView.
The current bottleneck in metanephric mesenchyme (MM)‐derived nephron organoid development is the absence of a connected network of collecting ducts (CD) derived from the ureteric bud (UB). To address this limitation, this study proposes a hypoxia‐based differentiation method that mimics the natural renal developmental environment, enabling the ...
Hyeonji Lim, Dohui Kim, Haejin Yoon, Joo H. Kang, Yong Jun Kim, Dong Sung Kim, Tae‐Eun Park   +6 more
wiley   +1 more source

Rheumatoid arthritis is caused by Proteus the molecular mimicry theory and Karl Popper [PDF]

, 2009
Alan Ebringer
openalex   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Molecular Mimicry Impact of the COVID-19 Pandemic: Sequence Homology Between SARS-CoV-2 and Autoimmune Diseases Epitopes. [PDF]

Immunoinformatics (Amst)
Maldonado-Catala P, Gouripeddi R, Schlesinger N, Facelli JC.   +3 more
europepmc   +1 more source

Human cytomegalovirus deploys molecular mimicry to recruit VPS4A to sites of virus assembly. [PDF]

PLoS Pathog
Butt BG, Fischer D, Rep AR, Schauflinger M, Read C, Böck T, Hirner M, Wienen F, Graham SC, von Einem J.   +9 more
europepmc   +2 more sources

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

Advanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen, Fushuai Peng, Shuqing Chen, Yukun Du, Jianyi Li, Yuanyuan Fan, Zichen Cui, Guanghui Gu, Han Zhang, Zhensong Jiang, Guodong Wang, Xingzhi Jing, Jun Dong, Tao Li, Yongming Xi   +14 more
wiley   +1 more source

Cognitive Impact of Neurotropic Pathogens: Investigating Molecular Mimicry through Computational Methods. [PDF]

Cell Mol Neurobiol
Büttiker P, Boukherissa A, Weissenberger S, Ptacek R, Anders M, Raboch J, Stefano GB.   +6 more
europepmc   +1 more source

Pectin Metabolism Influences Phloem Architecture and Flowering Time in Arabidopsis Thaliana

Advanced Science, EarlyView.
Cell wall remodeling mediated by changes in pectic homogalacturonan, including its methyl‐esterification status and degradation, shapes wall architecture. This study finds that pectin metabolism dynamically modulates wall properties and triggers auxin responses, which influence phloem morphogenesis and function, mediating the long‐distance transport of
Qing Zhang, Juan Du, Shuang Hao, Zhengmei Leng, Weiguo Liu, Chengjian Zhao, Yue Yu, Longquan Chen, Charles T. Anderson, Chaowen Xiao   +9 more
wiley   +1 more source

Faculty Opinions recommendation of Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis.

, 2008
Heinz Regele
openalex   +3 more sources

Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicry. [PDF]

EBioMedicine
Ma X, Zhang J, Jiang Q, Li YX, Yang G.
europepmc   +1 more source