Results 41 to 50 of about 4,511,721 (218)

SARS-CoV-2-Induced Immunosuppression: A Molecular Mimicry Syndrome

Global Medical Genetics, 2022
Background Contrary to immunological expectations, decay of adaptive responses against severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) characterizes recovered patients compared with patients who had a severe disease course or died following ...
Darja Kanduc
doaj   +1 more source

Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells [PDF]

, 2016
Indexación: Web of ScienceTumor angiogenesis is widely recognized as one of the hallmarks of cancer. Consequently, during the last decades the development and testing of commercial angiogenic inhibitors has been a central focus for both basic and ...
Carrasco-Avino, G, Corvalan, AH, Owen, GI, Pinto, MP, Sotomayor, P   +4 more
core   +1 more source

Molecular Mimicry between Respiratory Syncytial Virus F Antigen and the Human Proteome

Global Medical Genetics, 2023
This study examined respiratory syncytial virus (RSV) F glycoprotein (gp) antigen for molecular mimicry with the human proteome. It was found that the viral antigen presents an impressive number of pentapeptides (namely, 525 out of 570) in common with ...
Darja Kanduc
doaj   +1 more source

SARS-CoV-2 and Guillain-Barré syndrome: molecular mimicry with human heat shock proteins as potential pathogenic mechanism

Cell stress & chaperones (Print), 2020
Severe acute respiratory syndrome-related coronavirus 2 infection has been associated with Guillain-Barré syndrome. We investigated here the potential mechanism underlying the virus-induced damage of the peripheral nervous systems by searching the viral ...
G. Lucchese, A. Flöel
semanticscholar   +1 more source

Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase [PDF]

, 2013
Uracil-DNA glycosylase (UDG) compromises the replication strategies of diverse viruses from unrelated lineages. Virally encoded proteins therefore exist to limit, inhibit or target UDG activity for proteolysis.
A. R. Cole, Acharya, Barrett, Berkner, Broennimann, dos Reis, Duncan, Emsley, Freitag, G. Baltulionis, Haushalter, Hennessy, Huang, Jern, K. Ryzhenkova, Kabsch, Katz, Kiljunen, Kleywegt, Koulis, Martomo, McCoy, Newman, P. Hornyak, Pearl, Perez-Lago, Putnam, Putnam, R. Savva, S. Ofer, Savva, Savva, Savva, Schorman, Sharp, Takahashi, Tye, Warner, Warren, Winn   +39 more
core   +1 more source

Role of Mycobacterium paratuberculosis infection in etiopathogenesis of type 1 diabetes: A review of population-based studies

Journal of Diabetology, 2023
Introduction: Multiple mechanisms were proposed for the etiopathogenesis of type 1 diabetes mellitus (T1DM). An interplay between genetic, environmental, and immunological factors leads to generate autoantibodies against glutamic acid decarboxylase 65 ...
Ashish Gautam, Shoor Vir Singh, Saurabh Gupta, Nikhil Pursnani, Prabhat Agrawal   +4 more
doaj   +1 more source

Guillain-Barré syndrome: a century of progress [PDF]

, 2016
In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts — novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS).
A Campbell, A Chiba, A Chiba, A Pestronk, A Uncini, AA Ilyas, AD Langmuir, AJ Sumner, AK Asbury, AK Asbury, AK Asbury, AM Fitzpatrick, B Parra, B van den Berg, BH Waksman, C Brechenmacher, C Fokke, C Hafer-Macko, C Linington, CE Hafer-Macko, CL Schengrund, CP O'Leary, E Díez-Tejedor, FG van der Meché, FH Geisler, G Guillain, GM McKhann, GM O'Hanlon, H Wis´niewski, HJ Willison, Hugh J. Willison, J Kaldor, J Matias-Guiu, JA Goodfellow, JC Dodge, JG McLeod, JH Rees, JJ Plomp, JM Pearce, John A. Goodfellow, JW Albers, JW Griffin, JW Prineas, K Kaida, K Susuki, KE Astrom, KM Rhodes, KN Greenshields, LB Schonberger, LD Osler, LM Araujo, LT Kurland, M Fisher, M Kadlubowski, M Vermeulen, MK White, N Shahrizaila, N Yuki, N Yuki, N Yuki, N Yuki, NA Gregson, O Landry, PA van Doorn, PO Osterman, R McGonigal, R McGonigal, R van Koningsveld, RA Hughes, RA Hughes, RJ Greenwood, RP Kleyweg, S Draganescu, S Kusunoki, S Lafontaine, S Rinaldi, S Rinaldi, S Rinaldi, SK Halstead, SK Halstead, SK Halstead, T Lasky, T Saida, TE Feasby, TE Feasby, TW Ho, TW Ho, VM Cao-Lormeau, W Wiederholt, W Yan, WE Haymaker, Y Nagai   +91 more
core   +1 more source

Molecular mimicry between Zika virus and central nervous system inflammatory demyelinating disorders: the role of NS5 Zika virus epitope and PLP autoantigens

Arquivos de Neuro-Psiquiatria, 2023
Background Evidence indicates a strong link between Zika virus (ZikV) and neurological complications. Acute myelitis, optic neuritis, polyneuropathy, and encephalomyelitis that mimic inflammatory idiopathic demyelination disorders (IIDD) after ZikV ...
Laise Carolina França, Fabrícia Lima Fontes-Dantas, Diogo Gomes Garcia, Amanda Dutra de Araújo, João Paulo da Costa Gonçalves, Cláudia Cecília da Silva Rêgo, Elielson Veloso da Silva, Osvaldo José Moreira do Nascimento, Fernanda Cristina Rueda Lopes, Alice Laschuk Herlinger, Renato Santana de Aguiar, Orlando da Costa Ferreira Junior, Fernando Faria Andrade Figueira, Jorge Paes Barreto Marcondes de Souza, Joelma Freire De Mesquita, Soniza Vieira Alves-Leon   +15 more
doaj   +1 more source

Human molecular chaperones share with SARS-CoV-2 antigenic epitopes potentially capable of eliciting autoimmunity against endothelial cells: possible role of molecular mimicry in COVID-19

Cell stress & chaperones (Print), 2020
Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), the cause of COVID-19 disease, has the potential to elicit autoimmunity because mimicry of human molecular chaperones by viral proteins.
A. Marino Gammazza, Sébastien Légaré, Giosuè Lo Bosco, A. Fucarino, F. Angileri, E. Conway de Macario, A. Macario, F. Cappello   +7 more
semanticscholar   +1 more source

Ancient origin and maternal inheritance of blue cuckoo eggs [PDF]

, 2016
Maternal inheritance via the female-specific W chromosome was long ago proposed as a potential solution to the evolutionary enigma of co-existing host-specific races (or 'gentes') in avian brood parasites.
Ekrem, Torbjørn, Fossøy, Frode, Liang, Wei, Moksnes, Arne, Møller, Anders P., Rutila, Jarkko, Røskaft, Eivin, Sorenson, Michael D., Stokke, Bård G., Takasu, Fugo, Yang, Canchao   +10 more
core   +3 more sources