Results 41 to 50 of about 2,281 (156)
Interference in melanoma CD248 function reduces vascular mimicry and metastasis
Journal of Biomedical Science, 2022 Background Tumor vascular mimicry is an emerging issue that affects patient survival while having no treatment at the current moment. Despite several factors implicated in vascular mimicry, little is known about stromal factors that modulate tumor ...
Cheng-Hsiang Kuo +5 more
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Molecular mimicry: Can epitope mimicry induce autoimmune disease? [PDF]
Immunology & Cell Biology, 1997 Mimicry of host antigens by infectious agents may induce cross‐reactive autoimmune responses to epitopes within host proteins which, in susceptible individuals, may tip the balance of immunological response versus tolerance toward response and subsequently lead to autoimmune disease. Epitope mimicry may indeed be involved in the pathogenesis of several
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Clinical Discernment, Bone Marrow, and Molecular Diagnostics Are Equally Important to Solve the Phenotypic Mimicry among Subtypes of Myeloproliferative Neoplasms [PDF]
, 2021 Susann Schulze +6 more
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Molecular mimicry: Basis for autoimmunity [PDF]
Indian Journal of Clinical Biochemistry, 2000 Structural similarity between a viral protein and a self-component can trigger an autoimmune response, which is the basis of molecular mimicry. Alternatively an invading virus can induce an inflammatory response which in turn can initiate an attack by hitherto dormant T cells on a specific self-antigen, a phenomenon which is referred to as Bystander ...
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Cancer Biology & MedicineMelanoma, the most aggressive form of skin cancer, remains a significant clinical challenge due to the high metastatic potential and drug resistance. This review explores the pivotal roles of angiogenesis and vasculogenic mimicry in melanoma progression ...
Simona Serratì +9 more
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Inflammasome Molecular Insights in Autoimmune Diseases
Current Issues in Molecular BiologyAutoimmune diseases (AIDs) emerge due to an irregular immune response towards self- and non-self-antigens. Inflammation commonly accompanies these conditions, with inflammatory factors and inflammasomes playing pivotal roles in their progression.
Monica Neamțu +9 more
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Frontiers in Microbiology, 2017 Understanding etiology of autoimmune diseases has been a great challenge for designing drugs and vaccines. The pathophysiology of many autoimmune diseases may be attributed to molecular mimicry provoked by microbes.
Susanta Pahari +6 more
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Anti-ganglioside anti-idiotypic vaccination: more than molecular mimicry.
Frontiers in Oncology, 2012 Surgery, chemotherapy, and radiation therapy are standard modalities for cancer treatment, but the effectiveness of these treatments has reached a plateau. Thus, other strategies are being explored to combine with the current treatment paradigms in order
Ana María eHernández +2 more
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Emerging strategies for targeting vasculogenic mimicry in breast cancer treatment
Discover OncologyBreast cancer represents the most commonly diagnosed malignancy worldwide and is the fourth leading cause of cancer-related mortality. Approximately 2.3 million new cases of breast cancer were diagnosed worldwide in 2022, accounting for 11.6% of all ...
Nare Sekoba +3 more
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EMoMiS: A Pipeline for Epitope-based Molecular Mimicry Search in Protein Structures with Applications to SARS-CoV-2 [PDF]
, 2022 Vitalii Stebliankin +10 more
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