Results 251 to 260 of about 358,120 (301)
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
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Journal of the American Chemical Society, 2021
Pumps and motors are essential components of the world as we know it. From the complex proteins that sustain our cells, to the mechanical marvels that power industries, much we take for granted is only possible because of pumps and motors. Although molecular pumps and motors have supported life for eons, it is only recently that chemists have made ...
Yuanning Feng +6 more
openaire +2 more sources
Pumps and motors are essential components of the world as we know it. From the complex proteins that sustain our cells, to the mechanical marvels that power industries, much we take for granted is only possible because of pumps and motors. Although molecular pumps and motors have supported life for eons, it is only recently that chemists have made ...
Yuanning Feng +6 more
openaire +2 more sources
Nature, 2003
Life implies movement. Most forms of movement in the living world are powered by tiny protein machines known as molecular motors. Among the best known are motors that use sophisticated intramolecular amplification mechanisms to take nanometre steps along protein tracks in the cytoplasm.
Manfred, Schliwa, Günther, Woehlke
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Life implies movement. Most forms of movement in the living world are powered by tiny protein machines known as molecular motors. Among the best known are motors that use sophisticated intramolecular amplification mechanisms to take nanometre steps along protein tracks in the cytoplasm.
Manfred, Schliwa, Günther, Woehlke
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The Physics of Molecular Motors
Accounts of Chemical Research, 2001Molecular motors convert chemical energy into mechanical force and movement. Operating at energies just above those of the thermal bath, these motors experience large fluctuations, and their physical description must be necessarily stochastic. Here, motor operation is described as a biased diffusion on a potential energy surface defined by the ...
C, Bustamante, D, Keller, G, Oster
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Physical Review Letters, 1995
We present a simple stochastical model for motor molecules that cooperate in large groups. This model could apply for actin-myosin motors in muscles and for motility assays with a high concentration of motor molecules. We calculate the dependence of the velocity on the applied force as a function of ATP concentration and show the existence of a ...
, Jülicher, , Prost
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We present a simple stochastical model for motor molecules that cooperate in large groups. This model could apply for actin-myosin motors in muscles and for motility assays with a high concentration of motor molecules. We calculate the dependence of the velocity on the applied force as a function of ATP concentration and show the existence of a ...
, Jülicher, , Prost
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Essays in Biochemistry, 2000
The contractile apparatus of muscle is a highly efficient and adaptable mechanism for producing movement and is exploited throughout the animal kingdom. Molecular biology is yielding important insights into the intricate functioning of muscular contraction, especially in the heart, and in explaining the genesis of inherited myopathies.
F D, Davison, L G, D'Cruz, W J, McKenna
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The contractile apparatus of muscle is a highly efficient and adaptable mechanism for producing movement and is exploited throughout the animal kingdom. Molecular biology is yielding important insights into the intricate functioning of muscular contraction, especially in the heart, and in explaining the genesis of inherited myopathies.
F D, Davison, L G, D'Cruz, W J, McKenna
openaire +2 more sources
Journal of Luminescence, 2001
An approach which has been recently introduced to construct microscopic engines is investigated. The main characteristic of the approach is the possibility to determine dynamically the direction of motion of the engines. The engines, which are moving objects on a substrate, are able to move translationally or rotationally and simultaneously perform ...
Porto, M., Urbakh, M., Klafter, J.
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An approach which has been recently introduced to construct microscopic engines is investigated. The main characteristic of the approach is the possibility to determine dynamically the direction of motion of the engines. The engines, which are moving objects on a substrate, are able to move translationally or rotationally and simultaneously perform ...
Porto, M., Urbakh, M., Klafter, J.
openaire +2 more sources
Science, 1999
ATP is the energy currency of the cell: hydrolysis of ATP into ADP and inorganic phosphate (P) releases energy. The enzyme responsible for generating this energy currency is the ATP synthase. In a Perspective, [Fillingame][1] discusses two new reports ([ Sambongi et al. ][2] and [ Stock et al.
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ATP is the energy currency of the cell: hydrolysis of ATP into ADP and inorganic phosphate (P) releases energy. The enzyme responsible for generating this energy currency is the ATP synthase. In a Perspective, [Fillingame][1] discusses two new reports ([ Sambongi et al. ][2] and [ Stock et al.
openaire +2 more sources