Results 241 to 250 of about 98,232 (273)
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
FEBS Open Bio, EarlyView.The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
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Nature, 2003
Life implies movement. Most forms of movement in the living world are powered by tiny protein machines known as molecular motors. Among the best known are motors that use sophisticated intramolecular amplification mechanisms to take nanometre steps along protein tracks in the cytoplasm.
Manfred, Schliwa, Günther, Woehlke
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Life implies movement. Most forms of movement in the living world are powered by tiny protein machines known as molecular motors. Among the best known are motors that use sophisticated intramolecular amplification mechanisms to take nanometre steps along protein tracks in the cytoplasm.
Manfred, Schliwa, Günther, Woehlke
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Physical Review Letters, 1995
We present a simple stochastical model for motor molecules that cooperate in large groups. This model could apply for actin-myosin motors in muscles and for motility assays with a high concentration of motor molecules. We calculate the dependence of the velocity on the applied force as a function of ATP concentration and show the existence of a ...
, Jülicher, , Prost
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We present a simple stochastical model for motor molecules that cooperate in large groups. This model could apply for actin-myosin motors in muscles and for motility assays with a high concentration of motor molecules. We calculate the dependence of the velocity on the applied force as a function of ATP concentration and show the existence of a ...
, Jülicher, , Prost
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Science, 1999
ATP is the energy currency of the cell: hydrolysis of ATP into ADP and inorganic phosphate (P) releases energy. The enzyme responsible for generating this energy currency is the ATP synthase. In a Perspective, [Fillingame][1] discusses two new reports ([ Sambongi et al. ][2] and [ Stock et al.
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ATP is the energy currency of the cell: hydrolysis of ATP into ADP and inorganic phosphate (P) releases energy. The enzyme responsible for generating this energy currency is the ATP synthase. In a Perspective, [Fillingame][1] discusses two new reports ([ Sambongi et al. ][2] and [ Stock et al.
openaire +2 more sources
Journal of the American Chemical Society, 2021
Pumps and motors are essential components of the world as we know it. From the complex proteins that sustain our cells, to the mechanical marvels that power industries, much we take for granted is only possible because of pumps and motors. Although molecular pumps and motors have supported life for eons, it is only recently that chemists have made ...
Yuanning Feng +6 more
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Pumps and motors are essential components of the world as we know it. From the complex proteins that sustain our cells, to the mechanical marvels that power industries, much we take for granted is only possible because of pumps and motors. Although molecular pumps and motors have supported life for eons, it is only recently that chemists have made ...
Yuanning Feng +6 more
openaire +2 more sources
2007
Abstract Every biologist has seen it and marveled. Some watch it for hours, spell-bound. Take an individual living cell—a human skin cell, for example and put it under a powerful microscope. What comes into view is a far cry from the vague “protoplasm,” the so-called living jelly, “the stuff of life” that was taught in high school ...
+4 more sources
Abstract Every biologist has seen it and marveled. Some watch it for hours, spell-bound. Take an individual living cell—a human skin cell, for example and put it under a powerful microscope. What comes into view is a far cry from the vague “protoplasm,” the so-called living jelly, “the stuff of life” that was taught in high school ...
+4 more sources
2005
The F-, V-, and A-adenosine triphosphatases (ATPases) represent a family of evolutionarily related ion pumps found in every living cell. They either function to synthesize adenosine triphosphate (ATP) at the expense of an ion gradient or they act as primary ion pumps establishing transmembrane ion motive force at the expense of ATP hydrolysis.
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The F-, V-, and A-adenosine triphosphatases (ATPases) represent a family of evolutionarily related ion pumps found in every living cell. They either function to synthesize adenosine triphosphate (ATP) at the expense of an ion gradient or they act as primary ion pumps establishing transmembrane ion motive force at the expense of ATP hydrolysis.
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Nature Neuroscience, 2001
The hypothesis that prestin is the molecular motor in outer hair cells has been strengthened by a recent paper in Science identifying an unusual molecular mechanism for the effect.
R, Meech, M, Holley
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The hypothesis that prestin is the molecular motor in outer hair cells has been strengthened by a recent paper in Science identifying an unusual molecular mechanism for the effect.
R, Meech, M, Holley
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Molecular motors: nature's nanomachines
IEE Proceedings - Nanobiotechnology, 2003Molecular motors are protein-based machines that convert chemical potential energy into mechanical work. This paper aims to introduce the non-specialist reader to molecular motors, in particular, acto-myosin, the prototype system for motor protein studies. These motors produce their driving force from changes in chemical potential arising directly from
M J A, Tyreman, J E, Molloy
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