Results 81 to 90 of about 11,611,859 (368)
The integration of LC-MS/MS molecular networking and in silico MS/MS fragmentation is an emerging method for dereplication of natural products. In the present study, a targeted isolation of natural products using a new in silico-based annotation tool ...
K. Kang+5 more
semanticscholar +1 more source
Networks in molecular evolution
Networks in molecular evolution properties of the RNA map were derived: "For sequence spaces of chain lengths n > 10 there are orders of magnitude more sequences than structures and hence, the map is many-to-one (as predicted analytically above)." "Few common and many rare structures." "In other words, for each arbitrarily chosen pair of structures ...
Peter Schuster, Peter F. Stadler
openaire +3 more sources
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Graph Theory and Networks in Biology [PDF]
In this paper, we present a survey of the use of graph theoretical techniques in Biology. In particular, we discuss recent work on identifying and modelling the structure of bio-molecular networks, as well as the application of centrality measures to ...
Mason, Oliver, Verwoerd, Mark
core +3 more sources
Aloe plant species have been used for centuries in traditional medicine and are reported to be an important source of natural products. However, despite the large number of species within the Aloe genus, only a few have been investigated ...
Célia Breaud+14 more
doaj +1 more source
Uncovering the molecular networks in periodontitis [PDF]
Periodontitis is a complex immune‐inflammatory disease that results from a preestablished infection in gingiva, mainly due to Gram‐negative bacteria that colonize deeper in gingival sulcus and latter periodontal pocket. Host inflammatory and immune responses have both protective and destructive roles.
Eva J. Helmerhorst+5 more
openaire +3 more sources
VOLTA: adVanced mOLecular neTwork Analysis
Abstract Motivation Network analysis is a powerful approach to investigate biological systems. It is often applied to study gene co-expression patterns derived from transcriptomics experiments.
Pavel Alisa+5 more
openaire +6 more sources
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Network approach towards understanding the crazing in glassy amorphous polymers
We have used molecular dynamics to simulate an amorphous glassy polymer with long chains to study deformation mechanism of crazing and associated void statistics.
Hassanali, Ali A.+5 more
core +1 more source
Designed-in molecular interactions lead to superior thermo-mechanical properties in nanocomposites [PDF]
The effect of the nanofiller chemistry on the mechanical behaviour of thermoset polymer matrix nanocomposites is investigated. The interaction between a crosslinked polymer resin and the reinforcing nanofibers driven by their chemistry is revealed by ...
Atılgan, Ali Rana+9 more
core +1 more source