Results 11 to 20 of about 4,441,106 (313)

Geriatric mental health: Recent trends in molecular neuroscience

open access: diamondIndian Journal of Psychiatry, 2010
Byline: T. Sathyanarayana Rao, B. Praveena, K. Jagannatha Rao For every eight seconds, a Baby Boomer turns 60 in the world. By 2015, nearly 15% of our population will be over 65 years of age.
TS Sathyanarayana Rao   +2 more
openalex   +2 more sources

BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology

open access: yesiScience, 2021
Summary: Alzheimer’s disease (AD) is the most common progressive neurodegenerative disease. However, the underlying molecular mechanism is incompletely understood.
Liansheng Zhang   +13 more
doaj   +1 more source

Neuronal SNAP-23 is critical for synaptic plasticity and spatial memory independently of NMDA receptor regulation

open access: yesiScience, 2023
Summary: SNARE-mediated membrane fusion plays a crucial role in presynaptic vesicle exocytosis and also in postsynaptic receptor delivery. The latter is considered particularly important for synaptic plasticity and learning and memory, yet the identity ...
Mengjia Huang   +16 more
doaj   +1 more source

Central synaptopathy is the most conserved feature of motor circuit pathology across spinal muscular atrophy mouse models

open access: yesiScience, 2021
Summary: Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by reduced survival motor neuron (SMN) protein. Recently, SMN dysfunction has been linked to individual aspects of motor circuit pathology in a severe SMA mouse model.
Jannik M. Buettner   +9 more
doaj   +1 more source

Transduction catalysis: Doxorubicin amplifies rAAV-mediated gene expression in the cortex of higher-order vertebrates

open access: yesiScience, 2021
Summary: Rapid and efficient gene transduction via recombinant adeno-associated viruses (rAAVs) is highly desirable across many basic and clinical research domains.
Hongliang Gong   +11 more
doaj   +1 more source

The temporal pattern of synaptic activation determines the longevity of structural plasticity at dendritic spines

open access: yesiScience, 2023
Summary: Learning is thought to involve physiological and structural changes at individual synapses. Synaptic plasticity has predominantly been studied using regular stimulation patterns, but neuronal activity in the brain normally follows a Poisson ...
Ali Özgür Argunsah, Inbal Israely
doaj   +1 more source

Home - About - Disclaimer - Privacy