Results 31 to 40 of about 4,381,034 (355)
Connecting Circuits with Networks in Addiction Neuroscience: A Salience Network Perspective
International Journal of Molecular Sciences, 2023 Human neuroimaging has demonstrated the existence of large-scale functional networks in the cerebral cortex consisting of topographically distant brain regions with functionally correlated activity.
Adriana K. Cushnie +2 more
semanticscholar +1 more source
Personality Neuroscience: An Emerging Field With Bright Prospects
Personality Science, 2022 Personality neuroscience is the study of persistent psychological individual differences, typically in the general population, using neuroscientific methods.
C. DeYoung +10 more
semanticscholar +1 more source
iScience, 2021 Summary: It is well established that long-term depression (LTD) can be initiated by either NMDA or mGluR activation. Here we report that sustained activation of GluK2 subunit-containing kainate receptors (KARs) leads to α-amino-3-hydroxy-5-methyl-4 ...
Jithin D. Nair +8 more
doaj +1 more source
Unifying the essential concepts of biological networks: biological insights and philosophical foundations [PDF]
, 2020 Over the last decades, network-based approaches have become highly popular in diverse fields of biology, including neuroscience, ecology, molecular biology and genetics.
Hilgetag, Claus +2 more
core +2 more sources
Emerging Molecular Targets for Anti-Epileptogenic and Epilepsy Modifying Drugs
International Journal of Molecular Sciences, 2023 The pharmacological treatment of epilepsy is purely symptomatic. Despite many decades of intensive research, causal treatment of this common neurologic disorder is still unavailable.
K. Łukasiuk, W. Lasoń
semanticscholar +1 more source
iScience, 2022 Summary: The organization of the postsynaptic density (PSD), a protein-dense semi-membraneless organelle, is mediated by numerous specific protein–protein interactions (PPIs) which constitute a functional postsynapse.
Nikolaj Riis Christensen +9 more
doaj +1 more source
Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model
iScience, 2022 Summary: Targeted therapies for epilepsies associated with the mTORC1 signaling negative regulator GATOR1 are lacking. NPRL2 is a subunit of the GATOR1 complex and mutations in GATOR1 subunits, including NPRL2, are associated with epilepsy.
Brianne Dentel +11 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2019 Background: Monoamine oxidases (MAOs) were discovered nearly a century ago. This article aims to analyze the research literature landscape associated with MAOs as privileged class of neuronal enzymes (neuroenzymes) with key functions in the processes of ...
Andy Wai Kan Yeung +3 more
semanticscholar +1 more source
Super-resolving Microscopy in Neuroscience.
Chemical Reviews, 2021 Fluorescence imaging techniques play a pivotal role in our understanding of the nervous system. The emergence of various super-resolution microscopy methods and specialized fluorescent probes enables direct insight into neuronal structure and protein ...
Christian Werner, M. Sauer, C. Geis
semanticscholar +1 more source
Structural basis for SARM1 inhibition and activation under energetic stress
eLife, 2020 SARM1, an executor of axonal degeneration, displays NADase activity that depletes the key cellular metabolite, NAD+, in response to nerve injury. The basis of SARM1 inhibition and its activation under stress conditions are still unknown. Here, we present
Michael Sporny +10 more
doaj +1 more source